SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant [x]
Filed by a Party other than the Registrant [ ]
Check the appropriate box:
[ ] Preliminary  Proxy Statement
[ ] Confidential, for Use of the Commission Only (as permitted by Rule
    14a-6(e)(2))
[x] Definitive Proxy Statement
[ ] Definitive  Additional  Materials
[ ] Soliciting Material pursuant to ss.240.14a-11(c) or ss.240.14a-12

                                  BioTime, Inc.
                 ______________________________________________
                (Name of Registrant as Specified In Its Charter)

      _____________________________________________________________________
     (Name of Person(s) Filing Proxy Statement if other than the Registrant)

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         pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the
         filing fee is calculated and state how it was determined):

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[ ]  Fee paid previously with preliminary materials.

[ ] Check box if any part of the fee is offset as provided by Exchange  Act Rule
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previously.  Identify the previous filing by registration  statement  number, or
the Form or Schedule and the date of its filing.

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1
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                                  BioTime, Inc
                               935 Pardee Street
                               Berkeley, CA 94710
                                 (510)845-9535
                               FAX (510)845-7914


                                                   June 13, 2000


Dear Shareholder:


         You are  cordially  invited  to  attend  the  1999  Annual  Meeting  of
Shareholders  of BioTime,  Inc.  which will be held on Monday,  July 17, 2000 at
10:00 a.m. at The  Ritz-Carlton  Hotel,  600  Stockton  Street,  San  Francisco,
California.

         The Notice and Proxy  Statement on the following  pages contain details
concerning  the business to come before the meeting.  Management  will report on
current  operations and there will be an opportunity  for discussion  concerning
the  Company and its  activities.  Please sign and return your proxy card in the
enclosed  envelope to ensure that your shares will be  represented  and voted at
the  meeting  even if you  cannot  attend.  You are urged to sign and return the
enclosed proxy card even if you plan to attend the meeting.

         I look forward to personally  meeting all  shareholders who are able to
attend.




                                           /s/Paul Segall
                                           Paul Segall, Ph. D.
                                           Chairman and Chief Executive Officer






                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                            To Be Held July 17, 2000

         NOTICE IS HEREBY  GIVEN that the  Annual  Meeting  of  Shareholders  of
BioTime,  Inc.  (the  "Company")  will be held at The  Ritz-Carlton  Hotel,  600
Stockton Street, San Francisco,  California,  on July 17, 2000 at 10:00 a.m. for
the following purposes:

         1. To elect eight (8) directors of the Company to hold office until the
         next  Annual  Meeting  of  Shareholders   and  until  their  respective
         successors are duly elected and qualified;

         2.  To  ratify  the  appointment  of  Deloitte  &  Touche  LLP  as  the
         independent  accountants  of the  Company  for the fiscal  year  ending
         December 31, 2000; and

         3. To  transact  such other  business as may  properly  come before the
         meeting or any adjournments of the meeting.

      The Board of Directors has fixed the close of business on Monday,  May 22,
2000, as the record date for determining shareholders entitled to receive notice
of and to vote at the Annual Meeting or any postponement or adjournment thereof.

      Whether or not you expect to attend the  meeting in person,  you are urged
to sign and date the enclosed  form of proxy and return it promptly so that your
shares of stock may be  represented  and voted at the meeting.  If you should be
present at the meeting, your proxy will be returned to you if you so request.

                                       By Order of the Board of Directors,


                                       /s/Judith Segall
                                       Judith Segall
                                       Vice President and Secretary

Berkeley, California
June 13, 2000








                                 PROXY STATEMENT

                         ANNUAL MEETING OF SHAREHOLDERS

                           To Be Held on July 17, 2000

      The accompanying  proxy is solicited by the Board of Directors of BioTime,
Inc., a California corporation (the "Company" or "BioTime") having its principal
offices at 935 Pardee Street, Berkeley,  California 94710, for use at the Annual
Meeting of  Shareholders of the Company (the "Meeting") to be held at 10:00 a.m.
on Monday,  July 17, 2000 at The Ritz-Carlton  Hotel,  600 Stockton Street,  San
Francisco,  California.  Properly executed proxies in the accompanying form that
are  received  at or before the  Meeting  will be voted in  accordance  with the
directions noted on the proxies. If no direction is indicated,  such shares will
be voted FOR (1) each nominee for election as director,  and (2) approval of the
appointment of Deloitte & Touche LLP as independent  accountants for the Company
for the fiscal year ending December 31, 2000.

      The enclosed proxy confers discretionary authority to vote with respect to
any and all of the  following  matters  that may come  before the  Meeting:  (1)
matters that the Company's  Board of Directors  does not know a reasonable  time
before  the  Meeting  are  to be  presented  at the  Meeting;  and  (2)  matters
incidental to the conduct of the Meeting.  Management does not intend to present
any business  for a vote at the Meeting  other than the matters set forth in the
accompanying  Notice of Annual  Meeting of  Shareholders,  and as of the date of
this Proxy  Statement,  no  shareholder  has  notified  the Company of any other
business that may properly come before the meeting.  If other matters  requiring
the vote of the  shareholders  properly come before the Meeting,  then it is the
intention of the persons  named in the attached  form of proxy to vote the proxy
held by them in accordance with their judgment on such matters.

      Only  shareholders  of record at the close of business on Monday,  May 22,
2000 are entitled to notice of and to vote at the Meeting.  On that date,  there
were  10,891,823 of the Company's  Common Shares issued and  outstanding,  which
constitutes the only class of voting securities of the Company outstanding. Each
of the  Company's  Common  Shares is  entitled  to one vote in the  election  of
directors and in all other matters that may be acted upon at the Meeting, except
that  shareholders  may elect to cumulate  votes in the  election of  directors.
Under  cumulative  voting,  each  shareholder  may  give one  candidate,  or may
distribute among two or more  candidates,  a number of votes equal to the number
of  directors to be elected  multiplied  by the number of Common  Shares  owned.
Shareholders may not cumulate votes unless at least one shareholder gives notice
of his or her  intention to cumulate  votes at the Meeting.  The enclosed  proxy
confers discretionary authority to cumulate votes.

      Any  shareholder  giving a proxy has the power to revoke that proxy at any
time before it is voted.  A proxy may be revoked by filing with the Secretary of
the Company either a written  revocation or a duly executed proxy bearing a date
subsequent to the date of the proxy being revoked, or by voting in person at the
Meeting.  Any shareholder may attend the Meeting and vote in person,  whether or
not such  shareholder  has previously  submitted a proxy,  but attendance at the
Meeting will not revoke a proxy unless the shareholder votes in person.

                                        1






      The Company will bear all of the costs of the  solicitation of proxies for
use at the  Meeting.  In  addition  to the  use  of the  mails,  proxies  may be
solicited by a personal interview, telephone and telegram by directors, officers
and  employees  of the  Company,  who will  undertake  such  activities  without
additional  compensation.   Banks,  brokerage  houses  and  other  institutions,
nominees or fiduciaries  will be requested to forward the proxy materials to the
beneficial  owners of the  Common  Shares  held of record  by such  persons  and
entities  and will be  reimbursed  for  their  reasonable  expense  incurred  in
connection with forwarding such material.

      This Proxy  Statement and the  accompanying  form of proxy are first being
sent or given to the Company's shareholders on or about June 13, 2000.

                              ELECTION OF DIRECTORS

      At the  Meeting,  eight  directors  will be elected  to hold  office for a
one-year  term until the 2000 Annual  Meeting of  Shareholders,  and until their
successors have been duly elected and qualified. All of the nominees named below
are incumbent directors.

      It is the  intention of the persons  named in the enclosed  proxy,  unless
such proxy specifies otherwise, to vote the shares represented by such proxy FOR
the  election of the  nominees  listed  below.  In the  unlikely  event that any
nominee  should be unable to serve as a director,  proxies may be voted in favor
of a substitute nominee designated by the Board of Directors.

Directors and Nominees

      Paul Segall,  Ph.D.,  57, is the Chairman and Chief Executive  Officer and
has served as a director of the Company since 1990. Dr. Segall  received a Ph.D.
in Physiology from the University of California at Berkeley in 1977.

      Ronald S. Barkin,  54, became  President of BioTime  during  October 1997,
after serving as Executive Vice President  since April 1997. Mr. Barkin has been
a director of the Company since 1990.  Before  becoming an executive  officer of
the Company, Mr. Barkin practiced civil and corporate law for more than 25 years
after getting a J.D. from Boalt Hall, University of California at Berkeley.

      Victoria  Bellport,  34, is the Chief Financial Officer and Vice President
and has been a director of the Company since 1990. Ms. Bellport  received a B.A.
in Biochemistry from the University of California at Berkeley in 1988.

      Hal Sternberg, Ph.D., 46, is the Vice President of Research and has been a
director of the Company since 1990. Dr.  Sternberg was a visiting  scientist and
research  Associate at the University of California at Berkeley from  1985-1988,
where he supervised a team of  researchers  studying  Alzheimer's  Disease.  Dr.
Sternberg  received his Ph.D. from the University of Maryland in Biochemistry in
1982.


                                        2






      Harold  Waitz,  Ph.D.,  58,  is the  Vice  President  of  Engineering  and
Regulatory  Affairs  and has been a  director  of the  Company  since  1990.  He
received his Ph.D.  in  Biophysics  and Medical  Physics from the  University of
California at Berkeley in 1983.

      Judith Segall, 46, is the Vice President of Technology and Secretary,  and
has been a director of the Company from 1990 through 1994, and from 1995 through
the present date. Ms. Segall received a B.S. in Nutrition and Clinical Dietetics
from the University of California at Berkeley in 1989.

      Jeffrey B. Nickel,  Ph.D.,  55, has been a director of the Company  during
since 1997.  Dr. Nickel is the President of Nickel  Consulting  through which he
has served as a consultant to companies in the  pharmaceutical and biotechnology
industries  since 1990.  Prior to starting his consulting  business,  Dr. Nickel
served in a number of management  positions for Syntex  Corporation  and Merck &
Company.  Dr.  Nickel  received  his Ph.D.  in Organic  Chemistry  from  Rutgers
University in 1970.

      Milton H. Dresner,  74, has been a director of the Company since 1998. Mr.
Dresner is Co- Chairman of the Highland  Companies,  a diversified  organization
engaged in the  development  and ownership of residential  and  industrial  real
estate. Mr. Dresner serves as a director of Avatar Holdings, Inc., a real estate
development  company,  and  Childtime  Learning  Centers,  Inc. a child care and
pre-school education services company.

Executive Officers

      Paul Segall, Ronald S. Barkin,  Victoria Bellport,  Hal Sternberg,  Harold
Waitz and Judith Segall are the only executive officers of BioTime.

      There are no family  relationships  among the directors or officers of the
Company, except that Paul Segall and Judith Segall are husband and wife.

Directors' Meetings, Compensation and Committees of the Board

      The Board of Directors  has an Audit  Committee,  the members of which are
Jeffrey  Nickel and Milton  Dresner.  The purpose of the Audit  Committee  is to
recommend the  engagement of the  Company's  independent  auditors and to review
their  performance,  the plan, scope and results of the audit, and the fees paid
to the corporation's  independent auditors. The Audit Committee also will review
the Company's accounting and financial reporting procedures and controls and all
transactions between the Company and its officers,  directors,  and shareholders
who beneficially own 5% or more of the Common Shares.

      The Company does not have a standing Nominating Committee. Nominees to the
Board of Directors are selected by the entire Board.

      The Board of Directors has a Stock Option  Committee that  administers the
Company's  1992 Stock Option Plan and makes grants of options to key  employees,
consultants,  scientific  advisory board members and independent  contractors of
the Company, but not to officers or directors of the

                                        3






Company.  The members of the Stock Option Committee are Paul Segall, Ronald S.
Barkin, and Victoria Bellport.  The Stock Option Committee was formed during
September 1992.

       During the fiscal year ended  December 31,  1999,  the Board of Directors
met nine times. No director attended fewer than 75% of the meetings of the Board
or any committee on which they served.

       Directors of the Company who are not  employees  receive an annual fee of
$20,000,  which may be paid in cash or in Common Shares,  at the election of the
director.  During the year ended December 31, 1999,  each director who was not a
Company  employee  also  received  options to  purchase  10,000  Common  Shares.
Directors of the Company and members of committees of the Board of Directors who
are  employees of the Company are  compensated  as employees  but do not receive
additional  compensation  for serving as directors or attending  meetings of the
Board or committees of the Board.  Directors are entitled to reimbursements  for
their  out-of-pocket  expenses  incurred in  attending  meetings of the Board or
committees of the Board.

Executive Compensation

       The  Company  has  entered  into  five-year  employment  agreements  (the
"Employment  Agreements")  with Paul Segall,  the  Chairman and Chief  Executive
Officer;  Victoria Bellport,  the Chief Financial Officer;  Judith Segall,  Vice
President of Technology and Corporate Secretary;  Hal Sternberg,  Vice President
of Research;  and Harold Waitz,  Vice  President of  Engineering  and Regulatory
Affairs.  The  Employment  Agreements  will expire on December  31, 2000 but may
terminate  prior to the end of the term if the employee (1) dies, (2) leaves the
Company,  (3) becomes disabled for a period of 90 days in any 150 day period, or
(4) is  discharged  by the  Board of  Directors  for  failure  to carry  out the
reasonable policies of the Board, persistent  absenteeism,  or a material breach
of a  covenant.  Under the  Employment  Agreements,  as amended,  the  executive
officers are presently receiving an annual salary of $163,000,  and will receive
a one-time cash bonus of $25,000 if the Company  receives at least $1,000,000 of
equity financing from a pharmaceutical company.

       In the event of an  executive  officer's  death during the term of his or
her  Employment  Agreement,  the  Company  will pay his or her estate his or her
salary for a period of six months or until  December  31, 2000, whichever  first
occurs.  In  the  event  that  an  executive  officer's  employment  terminates,
voluntarily or  involuntarily,  after a change in control of the Company through
an acquisition of voting stock,  an  acquisition of the Company's  assets,  or a
merger or consolidation of the Company with another  corporation or entity,  the
executive  officer  will be  entitled  to  severance  compensation  equal to the
greater  of (a)  2.99  times  his or her  average  annual  compensation  for the
preceding  five  years and (b) the  balance  of his or her base  salary  for the
unexpired portion of the term of his Employment Agreement.

      The Company also entered into a similar  employment  agreement with Ronald
S. Barkin, which commenced on April 1, 1997 and expires on March 31, 2002.

       Each  executive  officer  has  also  executed  an  Intellectual  Property
Agreement  which  provides  that the  Company  is the  owner  of all  inventions
developed by the executive officer during the course of his or her employment.

                                        4







Insider Participation in Compensation Decisions

      The Board of Directors  does not have a standing  Compensation  Committee.
Instead, the Board of Directors as a whole approves all executive  compensation.
All of the executive officers of the Company serve on the Board of Directors but
do not vote on  matters  pertaining  to their own  personal  compensation.  Paul
Segall  and  Judith  Segall do not vote on matters  pertaining  to each  other's
compensation.

Board of Directors Report on Executive Compensation

      The compensation  policies implemented by the Board of Directors have been
influenced by the need to attract and retain  executives with the scientific and
management  expertise to conduct the Company's product  development program in a
highly  competitive  industry  dominated  by  larger,  more  highly  capitalized
companies.  Executive  compensation  is also influenced by the cost of living in
the San  Francisco  Bay Area.  Executive  compensation  may be composed of three
major  components:  (i) base salary;  (ii) annual  variable  performance  awards
payable in cash and tied to the Company's attainment of corporate objectives and
the officer's  achievement of personal goals;  and (iii)  long-term  stock-based
incentive  awards  (stock  options)  designed to  strengthen  the  mutuality  of
interests between the executive officers and the Company's shareholders.

      The Company entered into five-year employment  agreements with each of its
executive  officers in order to assure that their  services would continue to be
available  at a  pre-determined  base  salary  during a  critical  period in the
development of the Company's products and technology. The base salaries fixed by
the Employment  Agreements  were raised during May 1999 to bring them within the
median salary range for small to medium market capitalization  biotechnology and
drug development companies in the same geographic area as the Company.

      An annual  bonus may be earned by each  executive  officer  based upon the
achievement of personal and Company performance goals. Because the Company is in
the  development  stage,  the use of  performance  milestones  based upon profit
levels and return on equity as the basis for such incentive compensation has not
been considered appropriate. Instead, the incentive awards have been tied to the
achievement  of  personal  and  corporate   performance   targets.  The  Company
performance goals vary from year to year according to the stage of the Company's
operations.  Important  milestones  that  have been  considered  by the Board of
Directors  in  determining  incentive  bonuses  have  been  (i)  procurement  of
additional capital, (ii) licensing Company products,  (iii) completing specified
research and development  goals, and (iv) achievement of certain  organizational
goals.  Personal  goals are  related to the  functional  responsibility  of each
executive  officer.  The Board of Directors as a whole determines whether or not
each Company  performance  goal has been achieved.  During the fiscal year ended
December  31,  1999,  the Board of  Directors  did not award any cash bonuses or
grant any stock options to the executive officers.

                                        5






       The  following  table  summarizes  certain  information   concerning  the
compensation  paid to the  Company's  five  most  highly  compensated  executive
officers  during the last three fiscal  years and the six months ended  December
31, 1998.

                           SUMMARY COMPENSATION TABLE
Long-Term Compensation Stock Options Annual Compensation ------------- Name and Principal Position Year Ended Salary($) Bonus (Shares) - --------------------------- ---------- --------- ----- -------- Paul Segall December 31, 1999 $156,000 Chairman and Chief Executive December 31, 1998* $ 49,500 Officer June 30, 1998 $ 95,500 $50,000 __ June 30, 1997 $ 90,583 __ __ Hal Sternberg Vice President of Research December 31, 1999 $156,000 December 31, 1998* $ 49,500 June 30, 1998 $ 95,500 $25,000 __ June 30, 1997 $ 90,583 $25,000 __ Harold Waitz December 31, 1999 $156,000 Vice President of Engineering and December 31, 1998* $ 49,500 Regulatory Affairs June 30, 1998 $ 95,500 __ __ June 30, 1997 $ 90,583 $50,000 __ Victoria Bellport December 31, 1999 $156,000 Vice President and December 31, 1998* $ 49,500 Chief Financial Officer June 30, 1998 $ 95,500 $25,000 __ June 30, 1997 $ 90,583 $25,000 __ Judith Segall December 31, 1999 $156,000 Vice President and Corporate December 31, 1998* $ 49,500 Secretary June 30, 1998 $ 95,500 $25,000 __ June 30, 1997 $ 90,583 $25,000 __ *During 1998, the Company changed its fiscal year end from June 30 to December 31. The amounts of base salary shown in the table for the year ended December 31, 1998 reflect a short (six month) fiscal year.
6 Stock Options None of the five most highly compensated executive officers of the Company held any stock options during the fiscal year ended December 31, 1999. Certain Relationships and Related Transactions During the fiscal year ended December 31, 1999, $19,125 in fees for consulting services was paid to Jeffrey B. Nickel, a member of the Board of Directors. During September 1995, the Company entered into an agreement for financial advisory services with Greenbelt Corp., a corporation controlled by Alfred D. Kingsley and Gary K. Duberstein. Under this agreement the Company issued to the financial advisor warrants to purchase 311,276 Common Shares at a price of $1.93 per share, and the Company agreed to issue additional warrants to purchase up to an additional 622,549 Common Shares at a price equal to the greater of (a) 150% of the average market price of the Common Shares during the three months prior to issuance and (b) $2 per share. The additional warrants were issued in equal quarterly installments over a two year period, beginning October 15, 1995. The exercise price and number of Common Shares for which the warrants may be exercised are subject to adjustment to prevent dilution in the event of a stock split, combination, stock dividend, reclassification of shares, sale of assets, merger or similar transaction. The warrants are exercisable at the following prices: 466,912 at $1.93 per share; 77,818 at $2.35 per share; 77,818 at $9.65 per share; 77,818 at $9.42 per share; 77,818 at $10.49 per share; 77,818 at $15.74 per share; and 77,818 at $13.75 per share. The number of shares and exercise prices shown have been adjusted for the Company's subscription rights distribution during January 1997 and February 1999 and the payment of a stock dividend during October 1997. Under the agreement, upon the request of Greenbelt Corp., the Company will file a registration statement to register the warrants and underlying Common Shares for sale under the Securities Act of 1933, as amended (the "Act") and applicable state securities or "Blue Sky" laws. The Company will bear the expenses of registration, other than any underwriting discounts that may be incurred by Greenbelt Corp. in connection with a sale of the warrants or Common Shares. The Company shall not be obligated to file more than two such registration statements, other than registration statements on Form S-3. Greenbelt Corp. also is entitled to include warrants and Common Shares in any registration statement filed by the Company to register other securities for sale under the Act. During April 1998, the Company entered into a new financial advisory services agreement with Greenbelt Corp. The new agreement provides for an initial payment of $90,000 followed by an advisory fee of $15,000 per month that will be paid quarterly. The agreement expired on March 31, 2000, and a new agreement is being negotiated. The Company has agreed to reimburse Greenbelt Corp. for all reasonable out-of-pocket expenses incurred in connection with its engagement as financial advisor, and to indemnify Greenbelt Corp. and the officers, affiliates, employees, agents, assignees, and controlling person of Greenbelt Corp. from 7 any liabilities arising out of or in connection with actions taken on behalf of the Company under the agreement. Comparison of Shareholder Return The graph depicted below reflects a comparison of the cumulative total return (change in stock price plus reinvestment of dividends) of the Company's Common Shares with the cumulative total returns of the Nasdaq Stock Market Index, the BioCentury 100 Stock Index, and the Hambrecht & Quist Biotechnology Index. The BioCentury 100 Stock Index includes many companies in an early stage of development that have a market capitalization similar to BioTime's. The graph covers the period from July 1, 1994, the first day of the Company's fifth preceding fiscal year, through the fiscal year ended December 31, 1999. [GRAPH] The graph assumes that $100 was invested on July 1, 1994 in the Company's Common Shares and in each index and that all dividends were reinvested. No cash dividends have been declared on the Company's Common Shares.
7/1/94 6/30/95 6/30/96 6/30/98 6/30/98 12/31/98 12/31/99 ------ ------- ------- -------- ------- -------- -------- BioTime, Inc. 100.00 56.01 728.02 1,056.03 600.62 1,669.71 852.87 BioCentury 100 index 100.00 113.83 180.44 191.53 174.39 196.70 389.52 NASDAQ Index-US 100.00 133.43 171.31 208.34 274.31 321.46 580.75 H&Q Biotech 100.00 135.05 175.64 183.31 196.69 279.69 597.85
8 PRINCIPAL SHAREHOLDERS The following table sets forth information as of June 1, 2000 concerning beneficial ownership of Common Shares by each shareholder known by the Company to be the beneficial owner of 5% or more of the Company's Common Shares, and the Company's executive officers and directors. Information concerning certain beneficial owners of more than 5% of the Common Shares is based upon information disclosed by such owners in their reports on Schedule 13D or Schedule 13G. Number of Percent of Shares Total --------- ---------- Alfred D. Kingsley (1) Gary K. Duberstein Greenbelt Corp. Greenway Partners, L.P. Greenhouse Partners, L.P. 277 Park Avenue, 27th Floor New York, New York 10172 1,405,642 11.9% Paul and Judith Segall (2) 745,408 6.8 Harold D. Waitz (3) 524,166 4.8 Hal Sternberg 502,043 4.6 Victoria Bellport 205,978 1.9 Ronald S. Barkin (4) 192,761 1.7 Jeffrey B. Nickel (5) 35,000 * Milton H. Dresner (6) 39,497 * All officers and directors as a group (8 persons)(4)(5)(6) 2,244,853 20.3% - --------------------------- * Less than 1% (1) Includes 933,825 Common Shares issuable upon the exercise of certain warrants owned beneficially by Greenbelt Corp. and 59,730 Common Shares owned by Greenbelt Corp. Mr. Kingsley and Mr. Duberstein may be deemed to beneficially own the warrant shares that Greenbelt Corp. beneficially owns. Includes 90,750 Common Shares owned by Greenway 9 Partners, L.P. Greenhouse Partners, L.P. is the general partner of Greenway Partners, L.P. and Mr. Kingsley and Mr. Duberstein are the general partners of Greenhouse Partners, L.P. Greenhouse Partners, L.P., Mr. Kingsley and Mr. Duberstein may be deemed to beneficially own the Common Shares that Greenway Partners, L.P. beneficially owns. Includes 310,442 Common Shares owned solely by Mr. Kingsley, as to which Mr. Duberstein disclaims beneficial ownership. Includes 10,895 Common Shares owned solely by Mr. Duberstein, as to which Mr. Kingsley disclaims beneficial ownership. (2) Includes 543,245 shares held of record by Paul Segall and 202,163 shares held of record by Judith Segall. (3) Includes 2,100 shares held for the benefit of Dr. Waitz's minor children. (4) Includes 135,000 Common Shares issuable upon the exercise of certain options. (5) Includes 35,000 Common Shares issuable upon the exercise of certain options. (6) Includes 20,000 Common Shares issuable upon the exercise of certain options. Does not include Common Shares that Mr. Dresner may acquire in lieu of cash payment of his director's fees. COMPLIANCE WITH SECTION 16(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Section 16(a) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), requires the Company's directors and executive officers and persons who own more than ten percent (10%) of a registered class of the Company's equity securities to file with the Securities and Exchange Commission (the "SEC") initial reports of ownership and reports of changes in ownership of Common Shares and other equity securities of the Company. Officers, directors and greater than ten percent beneficial owners are required by SEC regulation to furnish the Company with copies of all reports they file under Section 16(a). To the Company's knowledge, based solely on its review of the copies of such reports furnished to the Company and written representations that no other reports were required, all Section 16(a) filing requirements applicable to its officers, directors and greater than ten percent beneficial owners were complied with during the fiscal year ended December 31, 1999. 10 RATIFICATION OF THE SELECTION OF INDEPENDENT ACCOUNTANTS The Board of Directors proposes and recommends that the shareholders ratify the selection of the firm of Deloitte & Touche LLP to serve as independent accountants of the Company for the fiscal year ending December 31, 2000. Deloitte & Touche LLP has served as the Company's independent accountants since 1991. Unless otherwise directed by the shareholders, proxies will be voted FOR approval of the selection of Deloitte & Touche LLP to audit the Company's consolidated financial statements. A representative of Deloitte & Touche LLP will attend the Meeting, and will have an opportunity to make a statement if he or she so desires and may respond to appropriate questions from shareholders. The Board of Directors Recommends a Vote "FOR" Ratification of the Selection of Deloitte & Touche LLP as the Company's Independent Accountants PROPOSALS OF SHAREHOLDERS Shareholders of the Company who intend to present a proposal for action at the 2000 Annual Meeting of Shareholders of the Company must notify the Company's management of such intention by notice received at the Company's principal executive offices not later than March 20, 2001 for such proposal to be included in the Company's proxy statement and form of proxy relating to such meeting. ANNUAL REPORT The Company's Annual Report on Form 10-K filed with the Securities and Exchange Commission for the fiscal year ended December 31, 1999, without exhibits, may be obtained by a shareholder without charge, upon written request to the Secretary of the Company. By Order of the Board of Directors, /s/Paul Segall Paul Segall, Ph.D. Chairman and Chief Executive Officer June 13, 2000 11 HOW TO ATTEND THE ANNUAL MEETING If you are a "shareholder of record" (meaning that you have a stock certificate registered in your own name), your name will appear on the Company's shareholder list. You will be admitted to the Meeting upon showing your proxy card, driver's license, or other identification. If you are a "street name" shareholder (meaning that your shares are held in an account at a broker-dealer firm) your name will not appear on the Company's shareholder list. If you plan to attend the Meeting, you should ask your broker for a "legal proxy." You will be admitted to the Meeting by showing your legal proxy. You probably received a proxy form from your broker along with your proxy statement, but that form can only be used by your broker to vote your shares, and it is not a "legal proxy" that will permit you to vote your shares directly at the Meeting. If you cannot obtain a legal proxy in time, you will be admitted to the Meeting if you bring a copy of your most recent brokerage account statement showing that you own BioTime stock. However, if you do not obtain a legal proxy, you can only vote your shares by returning to your broker, before the Meeting, the proxy form that accompanied your proxy statement. 12 PROXY FOR BIOTIME, INC. ANNUAL MEETING OF SHAREHOLDERS July 17, 2000 This Proxy is Solicited by the Board of Directors The undersigned appoints Paul Segall and Ronald S. Barkin, and each of them, with full power of substitution, as the undersigned's lawful agent and proxy to attend the Annual Meeting of Shareholders of BioTime, Inc. on July 17, 2000 and any adjournment thereof and to represent and vote all BioTime, Inc. Common Shares standing in the name of the undersigned upon the books of the corporation. DIRECTORS RECOMMEND A VOTE "FOR" PROPOSALS NUMBERED 1 AND 2 1) ELECTION OF [ ] FOR all nominees listed [ ] WITHHOLD AUTHORITY [ ] DIRECTORS at right (except as marked to vote for all to the contrary below) nominees listed at right. NOMINEES: RONALD S. BARKIN; VICTORIA BELLPORT; MILTON H. DRESNER; JEFFREY B. NICKEL; JUDITH SEGALL; PAUL SEGALL; HAL STERNBERG; HAROLD WAITZ **To withhold authority to vote for any individual nominee, draw a line through that person's name** FOR AGAINST ABSTAIN 2) RATIFYING THE APPOINTMENT OF INDEPENDENT [ ] [ ] [ ] ACCOUNTANTS The persons named as proxy may also vote on such other business as may properly come before the Meeting or any adjournment thereof. [ ] WISH TO ATTEND AND VOTE SHARES AT MEETING Please sign exactly as your shares are registered. _______________________ __________________ Persons signing as a corporate Signature Date officer or in a fiduciary capacity should indicate their _________________________ __________________ title or capacity. Signature if Held Jointly Date