form10q.htm
FORM
10-Q
SECURITIES
AND EXCHANGE COMMISSION
Washington,
D.C. 20549
(Mark
One)
T QUARTERLY
REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF
1934
For the
quarterly period ended September 30, 2009
OR
£ TRANSITION
REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF
1934
For the
transition period from
to
Commission
file number 1-12830
BioTime,
Inc.
(Exact
name of registrant as specified in its charter)
California
|
94-3127919
|
(State
or other jurisdiction of incorporation or organization)
|
(IRS
Employer Identification No.)
|
1301
Harbor Bay Parkway, Suite 100
Alameda,
California 94502
(Address
of principal executive offices)
(510)
521-3390
(Registrant's
telephone number, including area code)
Indicate
by check mark whether the registrant (1) has filed all reports required to be
filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the
preceding 12 months (or for such shorter period that the registrant was required
to file such reports), and (2) has been subject to such filing requirements for
the past 90 days.
T
Yes £
No
Indicate
by check mark whether the registrant is a large accelerated filer, an
accelerated filer, a non-accelerated filer, or a smaller reporting
company. See the definitions of “large accelerated filer,”
“accelerated filer” and “smaller reporting company” in Rule 12b-2 of the
Exchange Act).
Large accelerated filer
|
£
|
|
Accelerated
filer
|
£
|
Non-accelerated
filer
|
£
|
(Do
not check if a smaller reporting company)
|
Smaller reporting company
|
T
|
Indicate
by check mark whether the registrant is a shell company (as defined in Rule
12b-2 of the Exchange Act).
£ Yes T
No
APPLICABLE
ONLY TO CORPORATE ISSUERS:
Indicate
the number of shares outstanding of each of the issuer's classes of common
stock, as of the latest practicable date. 33,305,817 common shares,
no par value, as of November 10, 2009.
PART
1--FINANCIAL INFORMATION
Statements
made in this Report that are not historical facts may constitute forward-looking
statements that are subject to risks and uncertainties that could cause actual
results to differ materially from those discussed. Such risks and
uncertainties include but are not limited to those discussed in this report
under Item 1 of the Notes to Financial Statements, and in BioTime's Annual
Report on Form 10-K filed with the Securities and Exchange Commission. Words
such as “expects,” “may,” “will,” “anticipates,” “intends,” “plans,” “believes,”
“seeks,” “estimates,” and similar expressions identify forward-looking
statements.
Item
1. Financial Statements
BIOTIME,
INC.
CONDENSED
CONSOLIDATED BALANCE SHEETS
ASSETS
|
|
September 30,
2009
(unaudited)
|
|
|
December 31,
2008
|
|
CURRENT
ASSETS:
|
|
|
|
|
|
|
Cash
and cash equivalents
|
|
$ |
7,942,577 |
|
|
$ |
12,279 |
|
Accounts
receivable
|
|
|
134,848 |
|
|
|
2,748 |
|
Prepaid
expenses and other current assets
|
|
|
117,672 |
|
|
|
93,847 |
|
Total
current assets
|
|
|
8,195,097 |
|
|
|
108,874 |
|
|
|
|
|
|
|
|
|
|
Equipment,
net of accumulated depreciation of $626,122 and $602,510, for 2009 and
2008, respectively
|
|
|
114,215 |
|
|
|
105,607 |
|
Deferred
license fees
|
|
|
880,000 |
|
|
|
750,000 |
|
Deposits
|
|
|
76,902 |
|
|
|
70,976 |
|
TOTAL
ASSETS
|
|
$ |
9,266,214 |
|
|
$ |
1,035,457 |
|
|
|
|
|
|
|
|
|
|
LIABILITIES
AND SHAREHOLDERS' EQUITY (DEFICIT)
|
|
|
|
|
|
|
|
|
CURRENT
LIABILITIES:
|
|
|
|
|
|
|
|
|
Accounts
payable and accrued liabilities
|
|
$ |
709,070 |
|
|
$ |
1,179,914 |
|
Lines
of credit payable, net
|
|
|
135,455 |
|
|
|
1,885,699 |
|
Deferred
license revenue, current portion
|
|
|
292,904 |
|
|
|
312,904 |
|
Total
current liabilities
|
|
|
1,137,429 |
|
|
|
3,378,517 |
|
|
|
|
|
|
|
|
|
|
LONG-TERM
LIABILITIES:
|
|
|
|
|
|
|
|
|
Stock
appreciation rights compensation liability
|
|
|
2,684,013 |
|
|
|
483,688 |
|
Deferred
license revenue, net of current portion
|
|
|
1,297,049 |
|
|
|
1,516,727 |
|
Deferred
rent, net of current portion
|
|
|
1,263 |
|
|
|
3,339 |
|
Total
long-term liabilities
|
|
|
3,982,325 |
|
|
|
2,003,754 |
|
|
|
|
|
|
|
|
|
|
SHAREHOLDERS'
EQUITY (DEFICIT):
|
|
|
|
|
|
|
|
|
Common
stock, no par value, authorized 75,000,000 shares; issued and outstanding
33,038,883 and 25,076,798 shares at September 30, 2009 and December 31,
2008, respectively
|
|
|
58,242,566 |
|
|
|
43,184,606 |
|
Contributed
capital
|
|
|
93,972 |
|
|
|
93,972 |
|
Accumulated
deficit
|
|
|
(54,190,078 |
) |
|
|
(47,625,392 |
) |
Total
shareholders' equity (deficit)
|
|
|
4,146,460 |
|
|
|
(4,346,814 |
) |
TOTAL
LIABILITIES AND SHAREHOLDERS' EQUITY (DEFICIT)
|
|
$ |
9,266,214 |
|
|
$ |
1,035,457 |
|
See
accompanying notes to the condensed consolidated interim financial
statements.
BIOTIME,
INC.
CONDENSED
CONSOLIDATED STATEMENTS OF OPERATIONS
(Unaudited)
|
|
Three
Months Ended
|
|
|
Nine
Months Ended
|
|
|
|
September 30,
2009
|
|
|
September 30,
2008
|
|
|
September 30,
2009
|
|
|
September 30,
2008
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
REVENUES:
|
|
|
|
|
|
|
|
|
|
|
|
|
License
fees
|
|
$ |
73,226 |
|
|
$ |
70,850 |
|
|
$ |
219,678 |
|
|
$ |
204,728 |
|
Royalties
from product sales
|
|
|
225,518 |
|
|
|
341,391 |
|
|
|
799,910 |
|
|
|
991,444 |
|
Grant
income
|
|
|
144,899 |
|
|
|
- |
|
|
|
151,699 |
|
|
|
- |
|
Other
revenue
|
|
|
3,350 |
|
|
|
14,690 |
|
|
|
4,540 |
|
|
|
22,340 |
|
Total
revenues
|
|
|
446,993 |
|
|
|
426,931 |
|
|
|
1,175,827 |
|
|
|
1,218,512 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
EXPENSES:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research
and development
|
|
|
(744,201
|
) |
|
|
(548,478
|
) |
|
|
(1,909,619
|
) |
|
|
(1,312,607
|
) |
General
and administrative
|
|
|
(2,637,133
|
) |
|
|
(792,306
|
) |
|
|
(4,520,317
|
) |
|
|
(1,760,514
|
) |
Total
expenses
|
|
|
(3,381,334
|
) |
|
|
(1,340,784
|
) |
|
|
(6,429,936
|
) |
|
|
(3,073,121
|
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Loss
from operations
|
|
|
(2,934,341
|
) |
|
|
(913,853
|
) |
|
|
(5,254,109
|
) |
|
|
(1,854,609
|
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
OTHER
INCOME/(EXPENSE):
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Interest
expense
|
|
|
(653,664
|
) |
|
|
(164,945
|
) |
|
|
(1,326,367
|
) |
|
|
(367,995
|
) |
Loss
on sale of fixed assets
|
|
|
(1,159
|
) |
|
|
- |
|
|
|
(1,159
|
) |
|
|
- |
|
Other
income, net
|
|
|
14,409 |
|
|
|
1,604 |
|
|
|
17,296 |
|
|
|
6,669 |
|
Total
other expense, net
|
|
|
(640,414
|
) |
|
|
(163,341
|
) |
|
|
(1,310,230
|
) |
|
|
(361,326
|
) |
NET
LOSS
|
|
$ |
(3,574,755 |
) |
|
$ |
(1,077,194 |
) |
|
$ |
(6,564,339 |
) |
|
$ |
(2,215,935 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
NET
LOSS PER COMMON SHARE – BASIC AND DILUTED
|
|
$ |
(0.11 |
) |
|
$ |
(0.05 |
) |
|
$ |
(0.24 |
) |
|
$ |
(0.09 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
WEIGHTED
AVERAGE NUMBER OF COMMON SHARES OUTSTANDING: BASIC AND
DILUTED
|
|
|
31,283,312 |
|
|
|
23,738,939 |
|
|
|
27,912,812 |
|
|
|
23,492,987 |
|
See
accompanying notes to the condensed consolidated interim financial
statements.
BIOTIME,
INC.
CONDENSED
CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
|
|
Nine
months Ended
|
|
|
|
September 30,
2009
|
|
|
September 30,
2008
|
|
CASH
FLOWS FROM OPERATING ACTIVITIES:
|
|
|
|
|
|
|
Net
loss
|
|
$ |
(6,564,339 |
) |
|
$ |
(2,215,935 |
) |
Adjustments
to reconcile net loss to net cash used in operating
activities:
|
|
|
|
|
|
|
|
|
Depreciation
|
|
|
24,904 |
|
|
|
8,335 |
|
Loss
on write-off of fixed asset
|
|
|
1,159 |
|
|
|
– |
|
Write-off
of old receivables
|
|
|
2,538 |
|
|
|
– |
|
Reclassification
of licensing fees expensed in prior year
|
|
|
(10,000
|
) |
|
|
– |
|
Amortization
of deferred license revenues
|
|
|
(219,678
|
) |
|
|
(121,759
|
) |
Amortization
of deferred finance cost on lines of credit
|
|
|
762,644 |
|
|
|
188,221 |
|
Amortization
of deferred consulting fees
|
|
|
65,766 |
|
|
|
– |
|
Amortization
of deferred grant revenues
|
|
|
(20,000
|
) |
|
|
– |
|
Amortization
of deferred rent
|
|
|
(2,076
|
) |
|
|
2,999 |
|
Beneficial
conversion feature
|
|
|
302,953 |
|
|
|
– |
|
Stock
appreciation rights compensation liability
|
|
|
2,200,325 |
|
|
|
– |
|
Common
stock issued for services
|
|
|
– |
|
|
|
43,500 |
|
Stock-based
compensation
|
|
|
124,458 |
|
|
|
376,518 |
|
Options:
independent director compensation
|
|
|
141,907 |
|
|
|
– |
|
Warrants
issued for outside services
|
|
|
78,584 |
|
|
|
– |
|
Warrants
issued – interest expense (Line of Credit exchange offer)
|
|
|
190,845 |
|
|
|
– |
|
Changes
in operating assets and liabilities:
|
|
|
|
|
|
|
|
|
Accounts
receivable
|
|
|
(134,638
|
) |
|
|
(1,344
|
) |
Prepaid
expenses and other current assets
|
|
|
(74,872
|
) |
|
|
54,401 |
|
Accounts
payable and accrued liabilities
|
|
|
(241,691
|
) |
|
|
480,382 |
|
Accrued
interest on lines of credit
|
|
|
(43,158
|
) |
|
|
87,095 |
|
Other
liabilities
|
|
|
– |
|
|
|
5,026 |
|
Net
cash used in operating activities
|
|
|
(3,414,369
|
) |
|
|
(1,092,561
|
) |
|
|
|
|
|
|
|
|
|
CASH
FLOWS FROM INVESTING ACTIVITIES:
|
|
|
|
|
|
|
|
|
Payment
of royalty fee
|
|
|
– |
|
|
|
(750,000
|
) |
Purchase
of equipment
|
|
|
(34,671
|
) |
|
|
(1,390
|
) |
Security
deposit
|
|
|
(5,926
|
) |
|
|
(50,000
|
) |
Net
cash used in investing activities
|
|
|
(40,597
|
) |
|
|
(801,390
|
) |
|
|
|
|
|
|
|
|
|
CASH
FLOWS FROM FINANCING ACTIVITIES:
|
|
|
|
|
|
|
|
|
Repayment
on lines of credit
|
|
|
(263,825
|
) |
|
|
(21,802
|
) |
Borrowings
under lines of credit
|
|
|
2,310,000 |
|
|
|
1,858,334 |
|
Deferred
finance cost on lines of credit
|
|
|
(28,000
|
) |
|
|
– |
|
Employee
options exercised
|
|
|
653,750 |
|
|
|
– |
|
Director
options exercised
|
|
|
57,199 |
|
|
|
– |
|
Outside
consultant options exercised
|
|
|
137,500 |
|
|
|
– |
|
Warrants
exercised
|
|
|
518,640 |
|
|
|
– |
|
Proceeds
from issuance of common shares for cash
|
|
|
8,000,000 |
|
|
|
100,000 |
|
Net
cash provided by financing activities
|
|
|
11,385,264 |
|
|
|
1,936,532 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
NET
INCREASE IN CASH AND CASH EQUIVALENTS:
|
|
|
7,930,298 |
|
|
|
42,581 |
|
Cash
and cash equivalents at beginning of period
|
|
|
12,279 |
|
|
|
9,501 |
|
Cash
and cash equivalents at end of period
|
|
$ |
7,942,577 |
|
|
$ |
52,082 |
|
SUPPLEMENTAL
DISCLOSURE OF CASH FLOW INFORMATION
|
|
|
|
|
|
|
|
|
Cash
paid during the period for interest
|
|
$ |
415,290 |
|
|
$ |
59,389 |
|
SUPPLEMENTAL
SCHEDULE OF NON-CASH FINANCING AND INVESTING ACTIVITIES:
|
|
|
|
|
|
|
|
|
Issuance
of stock related to line of credit agreement
|
|
|
144,024 |
|
|
|
153,200 |
|
Common
shares issued for line of credit conversion
|
|
|
3,974,574 |
|
|
|
– |
|
Common
shares issued for line of credit extension
|
|
|
160,157 |
|
|
|
– |
|
Common
shares issued for outside services
|
|
|
– |
|
|
|
43,500 |
|
Common
shares issued for accounts payable
|
|
|
229,500 |
|
|
|
– |
|
Common
shares issued for deferred license fees
|
|
|
120,000 |
|
|
|
– |
|
Issuance
of warrants for new Line of Credit loans
|
|
|
207,703 |
|
|
|
– |
|
Issuance
of warrants for Line of Credit conversions
|
|
|
190,845 |
|
|
|
|
|
Warrants
issued for services
|
|
|
93,303 |
|
|
|
– |
|
Value
of rights to exchange promissory notes for stock
|
|
|
304,400 |
|
|
|
– |
|
See
accompanying notes to the condensed consolidated interim financial
statements.
BIOTIME,
INC.
NOTES
TO THE CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS
(UNAUDITED)
1. Organization,
Basis of Presentation, and Summary of Select Significant Accounting
Policies
General - BioTime is a
biotechnology company engaged in two areas of biomedical research and product
development. BioTime has historically developed blood plasma volume
expanders, and related technology for use in surgery, emergency trauma treatment
and other applications. Beginning in 2007, BioTime entered the
regenerative medicine business, focused on human embryonic stem (“hES”) cell and
induced pluripotent stem (“iPS”) cell technology. Products for the
research market are being developed and marketed through BioTime's wholly owned
subsidiary, Embryome Sciences, Inc. BioTime plans to develop stem
cell products for therapeutic use to treat cancer through its new subsidiary
OncoCyte Corporation, and through its subsidiary, BioTime Asia, Limited, in Hong
Kong.
Regenerative
medicine refers to therapies based on stem cell technology that are
designed to rebuild cell and tissue function lost due to degenerative disease or
injury. These novel stem cells provide a means of manufacturing every
cell type in the human body and therefore show considerable promise for the
development of a number of new therapeutic products. Embryome
Sciences is focusing its current efforts in the regenerative medicine field on
the development and sale of advanced human stem cell products and technology
that can be used by researchers at universities and other institutions, at
companies in the bioscience and biopharmaceutical industries, and at other
companies that provide research products to companies in those industries. These
research-only markets generally can be marketed without regulatory (FDA)
approval, and are therefore relatively near-term business opportunities when
compared to therapeutic products. In July
2009, Embryome Sciences, Inc., entered into an agreement under which Millipore
Corporation will become a worldwide distributor of ACTCellerate™ human progenitor
cell lines. Millipore’s initial offering of Embryome Sciences’
products will include six novel progenitor cell lines and optimized ESpan™ growth media for
the in vitro
propagation of each progenitor cell line. The companies anticipate
jointly launching 35 additional cell lines and associated ESpan™ growth media
within the coming 12 months.
BioTime’s
operating revenues have been derived almost exclusively from royalties and
licensing fees related to the sale of its plasma volume expander products,
primarily Hextend®. BioTime
began to make its first stem cell research products available during 2008 but
has not yet generated significant revenues in that business
segment. BioTime’s ability to generate substantial operating revenue
depends upon its success in developing and marketing or licensing its plasma
volume expanders and stem cell products and technology for medical and research
use. On April
29, 2009, the California Institute of Regenerative Medicine (“CIRM”) awarded
BioTime a $4,721,706 grant for a stem cell research project related to its
ACTCellerate™
technology. The CIRM grant covers the period of September 1, 2009
through August 31, 2012, and BioTime received the first quarterly payment in the
amount of $395,096 from CIRM on October 12, 2009.
The
unaudited condensed consolidated interim balance sheet as of September 30, 2009,
the unaudited condensed consolidated interim statements of operations for the
three and nine months ended September 30, 2009 and 2008, and the unaudited
condensed consolidated interim statements of cash flows for the nine months
ended September 30, 2009 and 2008 have been prepared by BioTime’s management in
accordance with the instructions from the Form 10-Q and Article 8-03 of
Regulation S-X. In the opinion of management, all adjustments
(consisting only of normal recurring adjustments) necessary to present fairly
the financial position, results of operations, and cash flows at September 30,
2009 and for all interim periods presented have been made. The
balance sheet as of December 31, 2008 is derived from BioTime's audited
financial statements as of that date. The results of operations for
the three and nine months ended September 30, 2009 are not necessarily
indicative of the operating results anticipated for the full year of
2009.
Certain
information and footnote disclosures normally included in financial statements
prepared in accordance with generally accepted accounting principles have been
condensed or omitted as permitted by regulations of the Securities and Exchange
Commission (“SEC”) except for the condensed consolidated balance sheet as of
December 31, 2008, which was derived from audited financial
statements. Certain previously furnished amounts have been
reclassified to conform with presentations made during the current
periods. It is suggested that these condensed consolidated interim
financial statements be read in conjunction with the annual audited financial
statements and notes thereto included in BioTime's Form 10-K for the year ended
December 31, 2008.
Principles of Consolidation –
The accompanying condensed consolidated interim financial statements include the
accounts of Embryome Sciences, Inc., a wholly-owned subsidiary of
BioTime. All material intercompany accounts and transactions have
been eliminated in consolidation. The condensed consolidated interim
financial statements are presented in accordance with accounting principles
generally accepted in the United States and with the accounting and reporting
requirements of Regulation S-X of the SEC.
Certain Significant Risks and
Uncertainties - BioTime’s operations are subject to a number of factors
that can affect its operating results and financial condition. Such
factors include but are not limited to the following: the results of clinical
trials of BioTime’s pharmaceutical products; BioTime’s ability to obtain United
States Food and Drug Administration and foreign regulatory approval to market
its pharmaceutical products; BioTime’s ability to develop new stem cell research
products and technologies; competition from products manufactured and sold or
being developed by other companies; the price and demand for BioTime products;
BioTime’s ability to obtain additional financing and the terms of any such
financing that may be obtained; BioTime’s ability to negotiate favorable
licensing or other manufacturing and marketing agreements for its products; the
availability of ingredients used in BioTime’s products; and the availability of
reimbursement for the cost of BioTime’s pharmaceutical products (and related
treatment) from government health administration authorities, private health
coverage insurers and other organizations.
Use of Estimates - The
preparation of unaudited condensed consolidated interim financial statements in
conformity with accounting principles generally accepted in the United States of
America requires management to make estimates and assumptions that affect the
reported amounts of assets and liabilities and disclosure of contingent assets
and liabilities at the date of the unaudited condensed consolidated interim
financial statements and the reported amounts of revenues and expenses during
the reporting period. Actual results could differ from those
estimates.
Subsequent Events - These
condensed consolidated interim financial statements were approved by management
and the Board of Directors and were issued on November 10,
2009. Subsequent events have been evaluated through this
date.
Effect of recently issued and
adopted accounting pronouncements –
In June
2009, the Financial Accounting Standards Board (“FASB”) approved the “FASB
Accounting Standards Codification” (“Codification”) as the single source of
authoritative, nongovernmental, U.S. Generally Accepted Accounting Principles
(“GAAP”) to be launched on July 1, 2009. The Codification does not
change current U.S. GAAP or how BioTime accounts for its transactions or the
nature of related disclosures made; instead it is intended to simplify user
access to all authoritative U.S. GAAP by providing all the authoritative
literature related to a particular topic in one place. All existing
accounting standard documents will be superseded, and all other accounting
literature not included in the Codification will be considered
non-authoritative. The Codification is effective for interim and
annual periods ending after September 15, 2009. The Codification is
effective for BioTime beginning with the quarter ending September 30, 2009 and
will not have an impact on its financial condition or results of
operations.
In
December 2007, the FASB issued an accounting pronouncement dealing with
non-controlling interests in consolidated financial statements. This
pronouncement requires that ownership interests in subsidiaries held by parties
other than the parent, and the amount of consolidated net income, be clearly
identified, labeled, and presented in the consolidated financial
statements. It also requires once a subsidiary is deconsolidated, any
retained non-controlling equity investment in the former subsidiary be initially
measured at fair value. Sufficient disclosures are required to
clearly identify and distinguish between the interests of the parent and the
interests of the non-controlling owners. It is effective for fiscal
years beginning after December 15, 2008, and requires retroactive adoption of
the presentation and disclosure requirements for existing minority
interests. All other requirements are applied
prospectively. BioTime does not anticipate that this accounting
pronouncement will have any material impact upon its preparation of its
financial statements.
In
January 2009, the FASB issued an accounting staff position on the subject of
impairment guidance which amended earlier such guidance. The goal of
this new staff position was to achieve more consistent determination of whether
an other-than-temporary impairment has occurred. This new guidance
also retains and emphasizes the objective of an other-than-temporary impairment
assessment provided in other related FASB guidance. This staff
position will be effective for interim and annual reporting periods ending after
December 15, 2009, and will be applied prospectively. BioTime does
not anticipate that this staff position will have any material impact upon its
preparation of its financial statements.
On April
1, 2009, the FASB issued an accounting staff position on the subject
of business combinations to address application issues raised by
preparers, auditors, and members of the legal profession on initial recognition
and measurement, subsequent measurement and accounting, and disclosure of assets
and liabilities arising from contingencies in a business
combination. This staff position will be effective for assets or
liabilities arising from contingencies in business combinations for which the
acquisition date is on or after the beginning of the first annual reporting
period beginning on or after December 15, 2008. BioTime does not
anticipate that this staff position will have any material impact upon its
preparation of its financial statements.
On April
9, 2009, the FASB issued an accounting staff position providing additional
guidance for estimating fair value of an asset or liability when the volume and
level of activity for the asset or liability have significantly
decreased. This staff position also includes guidance on identifying
circumstances that indicate a transaction is not orderly. This staff
position will be effective for interim and annual reporting periods ending after
June 15, 2009, and will be applied prospectively. BioTime does not
anticipate that this staff position will have any material impact upon its
preparation of its financial statements.
On April
9, 2009, the FASB issued an accounting staff position amending the
other-than-temporary impairment guidance in U.S. GAAP for debt securities to
make the guidance more operational and to improve the presentation and
disclosure of other-than-temporary impairments on debt and equity securities in
the financial statements. This staff position does not amend existing
recognition and measurement guidance related to other-than-temporary equity
securities. This staff position will be effective for interim and
annual reporting periods ending after June 15, 2009. BioTime does not
anticipate that this staff position will have any material impact upon its
preparation of its financial statements.
On April
9, 2009, the FASB issued an accounting staff position to require disclosures
about fair value of financial instruments for interim reporting periods of
publicly traded companies as well as in annual financial
statements. This staff position also amends earlier published FASB
guidance to require those disclosures in summarized financial information at
interim reporting periods. This staff position will be effective for
interim reporting periods ending after June 15, 2009. BioTime does
not anticipate that this staff position will have any material impact upon its
preparation of its financial statements.
In
June 2009, the FASB issued an accounting pronouncement which modifies how a
company determines when an entity that is insufficiently capitalized or is not
controlled through voting (or similar rights) should be
consolidated. This pronouncement clarifies that the determination of
whether a company is required to consolidate an entity shall be based on, among
other things, an entity’s purpose and design and a company’s ability to direct
the activities of the entity that most significantly impact the entity’s
economic performance. This pronouncement requires an ongoing
reassessment of whether a company is the primary beneficiary of a variable
interest entity. This pronouncement also requires additional
disclosures about a company’s involvement in variable interest entities and any
significant changes in risk exposure due to that involvement. This
pronouncement is effective for fiscal years beginning after November 15, 2009
and is effective for BioTime on January 1, 2010. BioTime is currently
evaluating the impact that the adoption of this pronouncement could have on its
financial condition, results of operations, and disclosures.
2. Lines
of Credit
BioTime
has a Revolving Line of Credit Agreement (the “Credit Agreement”) with certain
private lenders that is collateralized by a security interest in BioTime’s right
to receive royalty and other payments under its license agreement with Hospira,
Inc. BioTime may borrow up to $3,500,000 under the Credit
Agreement. Following an amendment to the Credit Agreement in April
2009, the maturity date of this Revolving Line of Credit was extended to
December 1, 2009 with respect to $2,669,282 in principal amount of
loans. BioTime repaid $223,834 of principal and accrued interest on
loans that matured on April 15, 2009 and were not extended. In
addition, from January 1 through April 15, 2009, certain lenders exercised their
right to exchange $624,415 of principal and accrued interest on loans for an
aggregate of 423,934 BioTime common shares. BioTime also received a
total of $2,310,000 of new loans under the amended Credit Agreement during the
period January 1 through May 19, 2009.
On August
20, 2009, BioTime completed an exchange offer with the holders of its revolving
credit notes, through which BioTime issued 1,989,515 common shares and warrants
to purchase 100,482 common shares in exchange for notes in the aggregate
principal amount of $3,349,259. BioTime also paid interest in the
aggregate amount of $294,351 on the revolving credit notes tendered in the
exchange offer. The revolving credit notes were held by lenders under
the Credit Agreement. The warrants issued in the exchange offer are
exercisable at a price of $2.00 per share, subject to adjustment under the terms
of a Warrant Agreement governing the warrants, and will expire at 5:00 p.m. EST
on October 31, 2010.
Revolving
credit notes in the amount of $150,000 remain outstanding and will be payable
with accrued interest upon maturity on December 1, 2009 unless converted into
equity by the note holder per the terms of the Credit Agreement. The
remaining lenders have the right to exchange their revolving credit notes for
BioTime common shares at a price of $2.00 per share, and for Embryome Sciences
common stock at $3.50 per share until December 1, 2009. The foregoing
per share exchange prices are subject to proportional adjustment in the event of
a stock split, reverse stock split, or similar event.
BioTime
has accrued interest of $6,800 as of September 30, 2009.
3. Deferred License
Fees
In
February 2009, BioTime’s wholly owned subsidiary, Embryome Sciences, Inc.,
entered into a Stem Cell Agreement with Reproductive Genetics Institute
(“RGI”). In partial consideration of the rights and licenses granted
to Embryome Sciences, Inc., by RGI, BioTime issued to RGI 32,259 common shares,
having a market value of $50,000 on the effective date of the Stem Cell
Agreement.
In March
2009, BioTime amended its license agreement with the Wisconsin Alumni Research
Foundation (“WARF”). The amendment increased the license fee from
$225,000 to $295,000, of which $225,000 is payable in cash and $70,000 was
payable by delivering BioTime common shares having a market value of $70,000 as
of March 2, 2009. The amendment extends until March 2, 2010 the dates
for payment of the $215,000 balance of the cash license fee and $20,000 in
remaining reimbursement of costs associated with preparing, filing and
maintaining the Licensed Patents by WARF to January 3, 2010. The
commencement date for payment of the annual $25,000 license maintenance fee has
also been extended to March 2, 2010.
4. Shareholders’
Equity (Deficit)
Total
shareholders' equity was increased by $8,493,274, from a deficit of $4,346,814
at December 31, 2008 to positive equity of $4,146,460 at September 30,
2009. This increase was due to issuances of BioTime common shares for
$8,000,000 in cash in May and July 2009 to two investors under Stock and Warrant
Purchase Agreements dated May 13, 2009, to the exercises of options at a total
value of $848,448, to the exercises of warrants at a total value of $518,640, to
debt converted to equity in the amount of $3,974,574, to shares issued for new
loan commitments of a total value of $144,024 during the period, to debt
extended in the amount of $160,157 in accordance with the Credit Agreement, to
valuation of options and warrants vested during the period for a total value of
$758,216, to the right of Credit Agreement lenders to exchange promissory notes
for common shares for a total value of $304,400, to the issuance of
common shares for financial adviser services in the amount of $229,500, and for
deferred license fees of $120,000. The impact of the reduction was
partially offset by net loss of $6,564,339 during the nine months ended
September 30, 2009.
5. Loss
Per Share
Basic
loss per share excludes dilution and is computed by dividing net loss by the
weighted average number of common shares outstanding during the
period. Diluted loss per share reflects the potential dilution from
securities and other contracts which are exercisable or convertible into common
shares. For the three and nine months ended September 30, 2009 and
2008, options to purchase 3,498,000 and 3,678,332 common shares, respectively,
and warrants to purchase 12,813,196 and 7,947,867, respectively, were excluded
from the computation of loss per share as their inclusion would be
antidilutive. As a result, there is no difference between basic and
diluted calculations of loss per share for all periods presented.
6. Subsequent
Events
In
October 2009, BioTime formed a new subsidiary, OncoCyte Corporation, which then
entered into a Stock Purchase Agreement under which it sold 3,000,000 of its
common shares, no par value, to Mr. George Karfunkel for $2,000,000 in cash,
representing a 15% interest in OncoCyte. Under the Stock Purchase
Agreement, Mr. Karfunkel has the right, but not the obligation, to purchase an
additional 3,000,000 OncoCyte common shares for $2,000,000 on or before April
15, 2010. Mr. Karfunkel beneficially owns more than 10% of the
outstanding common shares of BioTime. OncoCyte has agreed to file a
registration statement to register Mr. Karfunkel’s OncoCyte shares for sale
under the Securities Act of 1933, as amended (the “Securities Act”), upon his
request but not earlier than one year after OncoCyte completes an initial public
offering of its common shares. Mr. Karfunkel may also include his
shares in any registration statement filed by OncoCyte under the Securities Act
at any time after the completion of an initial public offering of OncoCyte
common shares, subject to certain exceptions and
limitations. OncoCyte will bear the costs of the registration
statements, including without limitation all registration and filing fees, fees
and expenses of compliance with securities or blue sky laws (including counsel’s
fees and expenses), printing expenses, messenger and delivery expenses, listing
fees and expenses, and fees and expenses of OncoCyte’s counsel, independent
accountants, and other persons retained or employed by OncoCyte. Mr.
Karfunkel will pay any underwriters discounts applicable to the sale of his
shares. OncoCyte and Mr. Karfunkel have agreed to indemnify each
other from certain liabilities, including liabilities under the Securities Act,
that may arise in connection with the sale of his shares under any such
registration statements.
In
October 2009, BioTime received royalties in the amount of $19,692 from CJ
CheilJedang Corp. (“CJ”), and received royalties in the amount of $257,388 from
Hospira. These amounts are based on sales of Hextend made by Hospira
and CJ in the third quarter of 2009, and will be reflected in BioTime’s
condensed consolidated interim financial statements for the fourth quarter of
2009.
In
October 2009, BioTime’s Board of Directors approved grants of a total of 30,000
incentive stock options to five new employees. These options have an
exercise price of $4.60, which was the last closing price of BioTime’s stock
immediately preceding this approval.
Between
September 30, 2009 and November 10, 2009, there were exercises of 266,934
BioTime warrants, yielding total proceeds to BioTime of
$533,868.
Item
2. Management's Discussion and Analysis of Financial Condition and
Results of Operations
MANAGEMENT'S
DISCUSSION AND ANALYSIS OF
FINANCIAL
CONDITION AND RESULTS OF OPERATIONS
Overview
We are a
biotechnology company engaged in two areas of biomedical research and product
development. We historically have developed blood plasma volume
expanders, and related technology for use in surgery, emergency trauma treatment
and other applications. Our lead blood plasma expander product,
Hextend®, is a
physiologically balanced intravenous solution used in the treatment of
hypovolemia. Hypovolemia is a condition caused by low blood volume,
often from blood loss during surgery or from injury. Hextend
maintains circulatory system fluid volume and blood pressure and keeps vital
organs perfused during surgery and trauma care.
We have
entered the regenerative medicine business focused on human embryonic stem
(“hES”) cell and induced pluripotent stem (“iPS”) cell
technology. Products for the research market are being developed and
marketed through our wholly owned subsidiary, Embryome Sciences,
Inc. We plan to develop stem cell products for
therapeutic use to treat cancer through our new subsidiary OncoCyte
Corporation, and through our subsidiary BioTime Asia, Limited in Hong
Kong.
.
Our
operating revenues have been derived almost exclusively from royalties and
licensing fees related to the sale of our plasma volume expander products,
primarily Hextend. We began to make our first stem cell research
products available during 2008, but we have not yet generated significant
revenues in that business segment. Our ability to generate
substantial operating revenue depends upon our success in developing and
marketing or licensing our plasma volume expanders and stem cell products and
technology for medical and research use.
Until
such time as we are able to successfully commercialize any of the various
regenerative medicine products and enter into commercial license agreements for
those products and additional foreign commercial license agreements for Hextend,
we will depend upon royalties from the sale of Hextend by Hospira and CJ as our
principal source of revenues.
Hextend® and
PentaLyte® are
registered trademarks of BioTime, Inc., and ESpan™,
ReCyte™, and
Espy™ are
trademarks of Embryome Sciences, Inc. ACTCellerate™ is a
trademark licensed to Embryome Sciences, Inc. by Advanced Cell Technology,
Inc.
Stem
Cells and Products for Regenerative Medicine Research
Regenerative
medicine refers to therapies based on hES cell technology that are designed to
rebuild cell and tissue function lost due to degenerative disease or
injury. hES cells are pluripotent, meaning they have the potential to
become any kind of cell found in the human body. Since embryonic stem
cells can now be derived in a noncontroversial manner, they are increasingly
likely to be utilized in a wide array of future therapies to restore the
function of organs damaged by degenerative diseases such as heart failure,
stroke, and diabetes.
Our
subsidiary, Embryome Sciences, is focusing its efforts in the regenerative
medicine field on the development and sale of advanced human stem cell products
and technology that can be used by researchers at universities and other
institutions, at companies in the bioscience and biopharmaceutical industries,
and at other companies that provide research products to companies in those
industries. These research-only products generally can be marketed without
regulatory (FDA) approval, and are therefore relatively near-term business
opportunities that we believe can be commercialized more quickly, using less
capital, than therapeutic products.
Embryome
Sciences has already introduced its first stem cell research products, and is
implementing plans to develop additional research products over the next two
years. One of the first products is a relational database that will permit
researchers to chart the cell lineages of human development, the genes expressed
in those cell types, and antigens present on the cell surface of those cells
that can be used in purification. This database will provide the first
detailed map of the embryome and will aid researchers in navigating the
complexities of human development and in identifying the many hundreds of cell
types coming from embryonic stem cells. Our embryome map data base is now
available at the website Embryome.com.
Embryome
Sciences acquired a license to use ACTCellerate™
technology and the rights to market approximately 100 progenitor cell types made
using ACTCellerate™
technology. ACTCellerate™
technology allows the rapid isolation of novel, highly-purified embryonic
progenitor cells (“hEPCs”). hEPCs are intermediate in the
developmental process between embryonic stem cells and fully differentiated
cells. hEPCs may possess the ability to become a wide array of cell
types with potential applications in research, drug discovery, and human
regenerative stem cell therapy.
Embryome
Sciences has entered into an agreement under which Millipore Corporation became
a worldwide distributor of ACTCellerate™ hEPC
lines. Millipore’s initial offering of Embryome Sciences’ products
will include six novel hEPC lines and optimized ESpan™
growth media for the in
vitro propagation of each hEPC line. The companies anticipate
jointly launching 35 cell lines and associated ESpan™
growth media within the coming 12 months. The Embryome Sciences
products distributed by Millipore may also be purchased directly from Embryome
Sciences at Embryome.com.
Embryome
Sciences also plans to offer for sale an array of hES cell lines carrying
inherited genetic diseases such as cystic fibrosis and muscular dystrophy. Other
new products that Embryome Sciences has targeted for development are ESpy™ cell
lines, which will be derivatives of hES cells that send beacons of light in
response to the activation of particular genes.
Embryome
Sciences also plans to bring to market new growth and differentiation factors
that will permit researchers to manufacture specific cell types from embryonic
stem cells, and purification tools useful to researchers in quality control of
products for regenerative medicine. As new products are developed,
they will become available for purchase on Embryome.com.
We have
also announced that we will organize a new subsidiary, BioTime Asia, Limited,
for the purpose of clinically developing and marketing therapeutic stem cell
products in Hong Kong, and marketing stem cell research products in China and
other countries in Asia. BioTime Asia will initially seek to develop
the therapeutic products for the treatment of ophthalmologic, skin,
musculo-skeletal system, and hematologic diseases, including the targeting of
genetically modified stem cells to tumors as a novel means of treating currently
incurable forms of cancer.
We have
engaged the services of Dr. Lu Daopei to facilitate BioTime Asia in arranging
and managing clinical trials of therapeutic stem cell products. Dr.
Lu is a world-renowned hematologist and expert in the field of hematopoietic
stem cell transplants who pioneered the first successful syngeneic bone marrow
stem cell transplant in the People’s Republic of China to treat aplastic anemia
and the first allogeneic peripheral blood stem cell transplant to treat acute
leukemia. Nanshan Memorial Medical Institute Limited (“NSMMI”), a
private Hong Kong company, has entered into an agreement with us under which
NSMMI will become a minority shareholder in BioTime Asia and will provide
BioTime Asia with its initial laboratory facilities and an agreed number of
research personnel, and will arrange financing for clinical trials.
BioTime
and our subsidiary, Embryome Sciences, Inc., will license the new venture rights
to use certain stem cell technology, and will sell the new venture stem cell
products for therapeutic use and for resale as research products. To
the extent permitted by law, BioTime Asia will license back to us for use
outside of China any new technology that BioTime Asia might develop or
acquire.
Our
obligations are subject to certain conditions and contingencies, including the
completion of feasibility studies for the venture. Either we or NSMMI
may terminate the agreement if certain clinical trial milestones are not met,
including the commencement of the first clinical trial of a therapeutic stem
cell product within two years.
During
October 2009, we organized OncoCyte Corporation for the purpose of developing
novel therapeutics for the treatment of cancer based on stem cell
technology. We and Embryome Sciences will license certain technology
to OncoCyte restricted to the field of cell-based cancer therapies, including
early patent filings on targeting stem cells to malignant
tumors. OncoCyte’s new therapeutic strategy and goal will be to
utilize human embryonic stem cell technology to create genetically modified stem
cells capable of homing to specific malignant tumors while carrying genes that
can cause the destruction of the cancer cells.
There is
no assurance that BioTime Asia or OncoCyte will be successful in developing any
new technology or stem cell products, or that any technology or products that
they may develop will be proven safe and effective in treating cancer or other
diseases in humans, or be successfully commercialized. Our potential
therapeutic products are at a very early stage of preclinical
development. Before any clinical trials can be conducted by BioTime
Asia or OncoCyte, they would have to compile sufficient laboratory test data
substantiating the characteristics and purity of the stem cells, conduct animal
studies, and then obtain all necessary regulatory and clinical trial site
approvals, and assemble a team of physicians and statisticians for the
trials.
On April
29, 2009, the California Institute of Regenerative Medicine (“CIRM”) awarded us
a $4,721,706 grant for a stem cell research project related to our
ACTCellerate™
technology. Our grant project is titled “Addressing the Cell Purity
and Identity Bottleneck through Generation and Expansion of Clonal Human
Embryonic Progenitor Cell Lines.” In our CIRM-funded research project
we will work with hEPCs generated using our ACTCellerate™
technology. The hEPCs are relatively easy to manufacture on a large
scale and in a purified state, which may make it advantageous to work with these
cells compared to the direct use of hES cells. We will work on
identifying antibodies and other cell purification reagents that may be useful
in the production of hEPCs that can be used to develop pure therapeutic cells
such as nerve, blood vessel, heart muscle, and cartilage, as well as other cell
types. The CIRM grant covers the period of September 1, 2009 through
August 31, 2012, and we received the first quarterly payment in the amount of
$395,096 from CIRM on October 12, 2009.
Plasma
Volume Expander Products
Our
principal product, Hextend, is a physiologically balanced blood plasma volume
expander, for the treatment of hypovolemia. Hextend is being
distributed in the United States by Hospira, Inc. and in South Korea by CJ
CheilJedang Corp. (“CJ”) under exclusive licenses from us. Summit
Pharmaceuticals International Corporation (“Summit”) has a license to develop
Hextend and PentaLyte in Japan, the People’s Republic of China, and
Taiwan. Summit will need to find a sublicensee or other source
of funding in order to complete clinical studies required to market
Hextend.
Hextend
has become the standard plasma volume expander at a number of prominent teaching
hospitals and leading medical centers and is part of the Tactical Combat
Casualty Care protocol. We believe that as Hextend use proliferates
within the leading U.S. hospitals, other smaller hospitals will follow their
lead, contributing to sales growth.
Results
of Operations
Revenues
Under our
license agreements, Hospira and CJ will report sales of Hextend and pay us the
royalties and license fees due on account of such sales after the end of each
calendar quarter. We recognize such revenues in the quarter in which
the sales report is received, rather than the quarter in which the sales took
place.
Our
royalty revenues for the three months ended September 30, 2009 consist of
royalties on sales of Hextend made by Hospira and CJ during the period beginning
April 1, 2009 and ending June 30, 2009. Royalty revenues recognized
for that three-month period were $225,518, a 34% decrease from the $341,391 of
royalty revenue during the same period last year. The decrease in
royalties reflects a decrease in sales to the United States Armed Forces, offset
somewhat by an increase in sales to hospitals. Purchases by the Armed
Forces generally take the form of intermittent, large volume orders, and cannot
be predicted with certainty.
We
received royalties of $19,692 from CJ and royalties of $257,388 from Hospira
during October 2009 based on sales of Hextend during the three months ended
September 30, 2009. This revenue will be reflected in our financial
statements for the fourth quarter of 2009. For the same period last
year, we received royalties of $19,887 from CJ and $212,009 from
Hospira. Royalties from CJ were included in license fees during prior
accounting periods.
We
recognized $73,226 and $70,865 of license fees from CJ and Summit during the
three months ended September 30, 2009 and September 30, 2008,
respectively. Full recognition of license fees has been deferred, and
is being recognized over the life of the contract, which has been estimated to
last until approximately 2019 based on the current expected life of the
governing patent covering our products in Korea and Japan.
On April
29, 2009, CIRM awarded us a $4,721,706 grant for a stem cell research project
related to our ACTCellerate™
technology. The CIRM grant covers the period of September 1, 2009
through August 31, 2012, and we received the first quarterly payment in the
amount of $395,096 from CIRM on October 12, 2009. We recognized
$131,699 of grant revenue for the three and nine months ended September 30,
2009.
Operating
Expenses
Research
and development expenses were $744,201 for the three months ended September 30,
2009, compared to $548,478 for the three months ended September 30,
2008. This increase is primarily attributable to an increase of
$62,149 in laboratory supplies and expenses, an increase of $101,473 in salaries
and related payroll fees and taxes allocated to research and development, an
increase of $61,840 in outside research expenses, and an increase of $35,795 in
stock-based compensation allocated to research and development. These
increases were offset to some extent by decreases in expenses allocated to
research and development of $16,999 for rent and of $48,042 for
insurance.
Research
and development expenses were $1,909,619 for the nine months ended September 30,
2009, compared to $1,312,607 for the nine months ended September 30,
2008. This increase is primarily attributable to an increase of
$198,429 in laboratory supplies and expenses, an increase of $108,998 in rent
allocated to research and development, an increase of $244,830 in salaries and
related payroll fees and taxes allocated to research and development, an
increase of $35,795 in stock-based compensation allocated to research and
development, and an increase of $88,975 in outside research
expenses. These increases were offset to some extent by a decrease of
$59,743 in insurance expense allocated to research and development.
Research
and development expenses include laboratory study expenses, salaries, rent,
insurance, and consultants’ fees.
General
and administrative expenses increased to $2,637,133 for the three months ended
September 30, 2009, from $792,306 for the three months ended September 30,
2008. This increase is primarily attributable to an increase of
$1,503,436 in stock appreciation rights compensation liability expenses, an
increase of $15,194 in general and administrative consulting fees, an increase
of $30,923 in expenses related to outside services, an increase of $43,963 in
legal fees, an increase of $201,407 in compensation to our independent
directors, an increase of $34,408 for expenses related to our Annual Meeting of
Shareholders, an increase of $56,957 for investor and public relations expenses,
and an increase of $23,270 for patent expenses. These increases were
offset in part by a decrease of $32,244 in accounting fees, and a decrease of
$64,271 in stock-based compensation expenses allocated to general and
administrative expense.
General
and administrative expenses increased to $4,520,317 for the nine months ended
September 30, 2009 from $1,760,514 for the nine months ended September 30,
2008. This increase is primarily attributable to an increase of
$1,968,702 in compensation liability expenses with respect to stock appreciation
rights granted to certain executive officers, an increase of $89,330 in outside
services, an increase of $24,544 in general and administrative consulting fees,
an increase of $37,435 in travel and entertainment expenses, an increase of
$27,249 in rent allocated to general and administrative costs, a net increase of
$246,722 in stock-based compensation expenses allocated to general and
administrative expense, an increase of $193,907 in compensation to our
independent directors, an increase of $34,408 for expenses related to our Annual
Meeting of Shareholders, an increase of $61,871 for investor and public
relations expenses, an increase of $35,485 in legal fees, an increase of $21,731
for patent expenses, and an increase in depreciation expense by
$16,572. These increases were offset in part by a decrease of $13,815
in office supplies and expenses, a decrease of $22,093 in accounting fees, a
decrease of $13,960 in licensing fees, and a decrease of $14,936 in insurance
expenses allocated to general and administrative expense.
Interest
and Other Income (Expense)
For the
three months ended September 30, 2009, we incurred a total of $653,664 of net
interest expense, compared to net interest expense of $164,945 for
the three months ended September 30, 2008. For the nine months ended
September 30, 2009, we incurred a total of $1,326,367 of net interest expense,
compared to net interest expense of $367,995 for
the nine months ended September 30, 2008. These increases for both
the three and nine months ended September 30, 2009 reflect an increase in
borrowings under our revolving line of credit. Interest expense also
includes an imputed cost arising from the right of Credit Agreement lenders to
exchange their promissory notes for BioTime common shares at a discounted price;
for the three and six months ended September 30, 2009, the imputed cost so
included in interest expense was $2,089 and $302,954,
respectively. Also, as part of our Line of Credit exchange offer
conducted in August 2009, we paid participating lenders interest that would have
been owed them through December 1, 2009. This interest paid for the
period of August 16, 2009 through December 1, 2009 equaled approximately
$118,000. See Note 2 to the condensed interim financial
statements.
Income
Taxes
During
the three months ended September 30, 2009 and 2008, there were no Federal and
state income taxes owed, since BioTime has substantial net operating loss
carryovers and has provided a 100% valuation allowance for any deferred
taxes.
Liquidity
and Capital Resources
Net cash
used in operations during the nine months ended September 30, 2009 amounted to
approximately $3,120,000. At September 30, 2009, we had $7,942,577 of
cash and cash equivalents on hand, and a line of credit for $3,500,000 from
which $150,000 remained drawn and still payable.
During
May and July, 2009, we raised $8,000,000 of equity capital through the sale of
4,400,000 common shares and 4,400,000 stock purchase warrants to two private
investors. The warrants entitle the investors to purchase additional
common shares at an exercise price of $2.00 per share. The warrants
will expire on October 31, 2010 and may not be exercised after that
date. See Note 6 to the condensed interim financial statements
for additional information.
During
October 2009, our subsidiary OncoCyte Corporation raised $2,000,000 through the
sale of 3,000,000 common shares to a private investor who also has the right,
but not the obligation, to acquire an additional 3,000,000 OncoCyte common
shares for $2,000,000 by April 15, 2009. The capital raised by
OncoCyte will be used to finance the initial stages of its research and
development program.
We have a
Revolving Line of Credit Agreement (the “Credit Agreement”) with certain private
lenders that is collateralized by a security interest in our right to receive
royalty and other payments under our license agreement with Hospira,
Inc. We may borrow up to $3,500,000 under the Credit
Agreement. Following an amendment to the Credit Agreement in April
2009, the maturity date of this Revolving Line of Credit was extended to
December 1, 2009 with respect to $2,669,282 in principal amount of
loans. We repaid $223,834 of principal and accrued interest on loans
that matured on April 15, 2009 and were not extended. In addition,
from January 1 through April 15, 2009, certain lenders exercised their right to
exchange $624,415 of principal and accrued interest on loans for an aggregate of
423,934 BioTime common shares. We also received a total of $2,310,000
of new loans under the amended Credit Agreement during the period January 1
through May 19, 2009.
On August
20, 2009, we completed an exchange offer with the holders of the revolving
credit notes, through which we issued 1,989,515 common shares and warrants to
purchase 100,482 common shares in exchange for revolving credit notes in the
aggregate principal amount of $3,349,259. We also paid interest in
the aggregate amount of $294,351 on the revolving credit notes tendered in the
exchange offer. The warrants issued in the exchange offer are
exercisable at a price of $2.00 per share, subject to adjustment under the terms
of a Warrant Agreement governing the warrants, and will expire at 5:00 p.m. EST
on October 31, 2010.
Revolving
credit notes in the amount of $150,000 remain outstanding and will be payable
with accrued interest upon maturity on December 1, 2009 unless converted into
equity by the note holder per the terms of the Credit Agreement. The
remaining lender has the right to exchange their promissory notes for BioTime
common shares at a price of $2.00 per share, and for Embryome Sciences common
stock at $3.50 per share until December 1, 2009. The foregoing per
share exchange prices are subject to proportional adjustment in the event of a
stock split, reverse stock split, or similar event.
In April
2009, CIRM awarded us a $4,721,706 grant for a stem cell research project
related to our ACTCellerate™ technology. CIRM will provide funding
for this research project over a period of three years, with approximately
$1,600,000 expected to be available during the first 12 months. The
CIRM grant covers the period of September 1, 2009 through August 31, 2012, and
we received the first quarterly payment in the amount of $395,096 from CIRM on
October 12, 2009, of which $131,699 is recognized as grant income for the three
and nine months ended September 30, 2009.
BioTime
had approximately 12.8 million warrants outstanding as of September 30,
2009. These warrants have an exercise price of $2.00 per warrant,
they expire on October 31, 2010, and they are callable under certain
conditions. These conditions include our common stock being traded on
a national exchange, public registration of the warrants (of which approximately
7.5 million are already currently registered), and the price of the shares
traded on a national exchange being $4.00 or greater for 20 consecutive
days.
There are
no current plans to call the warrants. If exercised, the warrants
would provide us with approximately $25 million of additional capital
resources.
Since
inception, we have primarily financed our operations through the sale of equity
securities, licensing fees, royalties on product sales by our licensees, and
borrowings. The amount of license fees and royalties that may be
earned through the licensing and sale of our products and technology, the timing
of the receipt of license fee payments, and the future availability and terms of
equity financing, are uncertain. Although we have recently been
awarded a research grant from CIRM for a particular project, we must finance our
other research and operations with funding from other
sources. Although OncoCyte has raised $2,000,000 to fund the start-up
of its initial research and development program, it will need to raise
substantial amounts of additional capital or to collaborate with another stem
cell or pharmaceutical development company to develop products in its field of
research. BioTime Asia will rely upon NSMMI to provide or raise
financing for its operations. The unavailability or inadequacy of
financing or revenues to meet future capital needs could force us to modify,
curtail, delay, or suspend some or all aspects of our planned
operations. Sales of additional equity securities could result in the
dilution of the interests of present shareholders.
We had no
contractual obligations as of September 30, 2009, with the exception of two
facilities lease agreements. We currently have a fixed,
non-cancelable operating lease on our office and laboratory facilities in
Emeryville, California (the “Emeryville lease”). Under the Emeryville
lease, we are committed to make payments of $11,127 per month, increasing 3%
annually, plus our pro rata share of operating costs for the building and office
complex, through May 31, 2010. In April 2008, we entered into a
sublease of approximately 11,000 square feet of office and research laboratory
spaced at 1301 Harbor Bay Parkway, in Alameda, California (the “Alameda
sublease”). We have now moved our headquarters to this new
facility. The Alameda sublease will expire on November 30,
2010. Base monthly rent was $22,000 during 2008, and will be $22,600
during 2009, and $23,340 during 2010. In addition to base rent, we
will pay a pro rata share of real property taxes and certain costs related to
the operation and maintenance of the building in which the subleased premises
are located.
Item
3. Quantitative and Qualitative Disclosures About Market
Risk
We did
not hold any market risk sensitive instruments as of September 30, 2009,
December 31, 2008, or September 30, 2008.
Item
4T. Controls and Procedures
Evaluation
of Disclosure Controls and Procedures
It is
management’s responsibility to establish and maintain “disclosure controls and
procedures” as such term is defined in Rule 13a-15 under the Securities Exchange
Act of 1934 (the “Exchange Act”). Our management, including our
principal executive officer, our principal operations officer, and our principal
financial officer, have reviewed and evaluated the effectiveness of our
disclosure controls and procedures as of a date within ninety (90) days of the
filing date of this Form 10-Q quarterly report. Following this review
and evaluation ,
management collectively determined that our disclosure controls and procedures
are effective to ensure that information required to be disclosed by us in
reports that we file or submit under the Exchange Act (i) is recorded,
processed, summarized, and reported within the time periods specified in SEC
rules and forms, and (ii) is accumulated and communicated to management,
including our chief executive officer, our chief operations officer, and our
chief financial officer, as appropriate to allow timely decisions regarding
required disclosure.
Changes
in Internal Controls
There
were no changes in our internal control over financial reporting that occurred
during the period covered by this Quarterly Report on Form 10-Q that have
materially affected, or are reasonably likely to materially affect, our internal
control over financial reporting.
PART
II - OTHER INFORMATION
Item
4. Submission of Matters to a Vote of Security Holders.
Our
annual meeting of shareholders was held on October 15, 2009. At the
meeting our shareholders elected nine directors to serve until the next annual
meeting and until their successors are duly elected and
qualified. Our shareholders also approved an amendment to our
articles of incorporation that increased the number of authorized common shares
from 50,000,000 to 75,000,000, and two amendments of our 2002 Employee Stock
Option Plan that made an additional 4,000,000 shares available for the grant of
stock options or the sale of restricted stock to our key employees, directors,
and consultants. The shareholders also ratified the Board of
Directors’ selection of Rothstein Kass & Company, P.C. as our independent
public accountants to audit our financial statements for the current fiscal
year. The following tables show the votes cast by our shareholders
and any abstentions and broker non-votes with respect to the matters presented
to shareholders for a vote at the meeting:
Election
of Directors
Nominee
|
Votes For
|
Percent of Vote
|
Votes Withheld
|
|
|
|
|
Neal
C. Bradsher
|
27,492,709
|
99.31%
|
190,802
|
Arnold
I. Burns
|
27,437,588
|
99.11%
|
245,923
|
Robert
N. Butler
|
27,487,411
|
99.29%
|
196,100
|
Abraham
E. Cohen
|
27,436,048
|
99.11%
|
247,463
|
Valeta
A. Gregg
|
27,516,693
|
99.40%
|
166,818
|
Alfred
D. Kingsley
|
27,514,388
|
99.39%
|
169,123
|
Pedro
Lichtinger
|
27,476,494
|
99.25%
|
207,017
|
Judith
Segall
|
27,517,747
|
99.40%
|
165,764
|
Michael
D. West
|
27,514,809
|
99.39%
|
168,702
|
Amendment
of Articles of Incorporation
|
Shares Voted
|
Percent of Quorum
|
|
|
|
For
|
27,289,482
|
98.58%
|
Against
|
315,238
|
|
Abstain
|
78,791
|
|
Broker
Non-Votes
|
-
|
|
Amendments
of 2002 Stock Option Plan
|
Shares Voted
|
Percent of Quorum
|
|
|
|
For
|
18,306,538
|
66.13%
|
Against
|
621,140
|
|
Abstain
|
41,252
|
|
Broker
Non-Votes
|
8,714,581
|
|
Ratification
of Appointment of Independent Accountants
|
Shares Voted
|
Percent of Quorum
|
|
|
|
For
|
27,555,842
|
99.54%
|
Against
|
68,694
|
|
Abstain
|
58,975
|
|
Broker
Non-Votes
|
-
|
|
Item
6. Exhibits
Exhibit
Numbers
|
|
Description
|
|
|
|
3.1
|
|
Articles
of Incorporation with all amendments.§
|
|
|
|
3.2
|
|
By-Laws,
As Amended.#
|
|
|
|
4.1
|
|
Specimen
of Common Share Certificate.+
|
|
|
|
4.2
|
|
Form
of Warrant Agreement between BioTime, Inc. and American Stock Transfer
& Trust Company++
|
|
|
|
4.3
|
|
Form
of Amendment to Warrant Agreement between BioTime, Inc. and American Stock
Transfer & Trust Company. +++
|
|
|
|
4.4
|
|
Form
of Warrant+++
|
|
|
|
4.5
|
|
Warrant
Agreement between BioTime, Inc., Broadwood Partners, L.P., and George
Karfunkel ~~
|
|
|
|
4.6
|
|
Form
of Warrant ~~
|
|
|
|
10.1
|
|
Intellectual
Property Agreement between BioTime, Inc. and Hal
Sternberg.+
|
|
|
|
10.2
|
|
Intellectual
Property Agreement between BioTime, Inc. and Harold
Waitz.+
|
|
|
|
10.3
|
|
Intellectual
Property Agreement between BioTime, Inc. and Judith
Segall.+
|
|
|
|
10.4
|
|
Intellectual
Property Agreement between BioTime, Inc. and Steven
Seinberg.*
|
|
|
|
10.5
|
|
Agreement
between CMSI and BioTime Officers Releasing Employment Agreements, Selling
Shares, and Transferring Non-Exclusive License.+
|
|
|
|
10.6
|
|
Agreement
for Trans Time, Inc. to Exchange CMSI Common Stock for BioTime, Inc.
Common Shares.+
|
|
|
|
10.7
|
|
2002
Stock Option Plan, as amended. §
|
|
|
|
10.8
|
|
Exclusive
License Agreement between Abbott Laboratories and BioTime,
Inc. (Portions of this exhibit have been omitted pursuant to a
request for confidential
treatment).##
|
10.9
|
|
Modification
of Exclusive License Agreement between Abbott Laboratories and BioTime,
Inc. (Portions of this exhibit have been omitted pursuant to a request for
confidential treatment).^
|
|
|
|
10.10
|
|
Exclusive
License Agreement between BioTime, Inc. and CJ Corp.**
|
|
|
|
10.11
|
|
Hextend
and PentaLyte Collaboration Agreement between BioTime, Inc. and Summit
Pharmaceuticals International Corporation.‡
|
|
|
|
10.12
|
|
Lease
dated as of May 4, 2005 between BioTime, Inc. and Hollis R& D
Associates ‡‡
|
|
|
|
10.13
|
|
Addendum
to Hextend and PentaLyte Collaboration Agreement Between BioTime Inc. And
Summit Pharmaceuticals International Corporation‡‡‡
|
|
|
|
10.14
|
|
Amendment
to Exclusive License Agreement Between BioTime, Inc. and Hospira,
Inc.††
|
|
|
|
10.15
|
|
Hextend
and PentaLyte China License Agreement Between BioTime, Inc. and Summit
Pharmaceuticals International Corporation.†††
|
|
|
|
10.16
|
|
Employment
Agreement, dated October 10, 2007, between BioTime, Inc. and Michael D.
West.++++
|
|
|
|
10.17
|
|
Commercial
License and Option Agreement between BioTime and Wisconsin Alumni Research
Foundation.****
|
|
|
|
10.18
|
|
Form
of Amended and Restated Revolving Credit Note.‡‡‡‡
|
|
|
|
10.19
|
|
Third
Amended and Restated Revolving Line of Credit Agreement, March 31,
2008.~
|
|
|
|
10.20
|
|
Third
Amended and Restated Security Agreement, dated March 31,
2008.~
|
|
|
|
10.21
|
|
Sublease
Agreement between BioTime, Inc. and Avigen, Inc.++++
|
|
|
|
10.22
|
|
License,
Product Production, and Distribution Agreement, dated June 19, 2008, among
Lifeline Cell Technology, LLC, BioTime, Inc., and Embryome Sciences, Inc.
^^
|
10.23
|
|
License
Agreement, dated July 10, 2008, between Embryome Sciences, Inc. and
Advanced Cell Technology, Inc. ^^
|
|
|
|
10.24
|
|
License
Agreement, dated August 15, between Embryome Sciences, Inc. and Advanced
Cell Technology, Inc. ^^^
|
|
|
|
10.25
|
|
Sublicense
Agreement, dated August 15, between Embryome Sciences, Inc. and Advanced
Cell Technology, Inc. ^^^
|
|
|
|
10.26
|
|
Fourth
Amendment of Revolving Line of Credit Agreement.^^^
|
|
|
|
10.27
|
|
Fourth
Amendment of Security Agreement.^^^
|
|
|
|
10.28
|
|
Stem
Cell Agreement, dated February 23, 2009, between Embryome Sciences, Inc.
and Reproductive Genetics Institute. ^^^^
|
|
|
|
10.29
|
|
First
Amendment of Commercial License and Option Agreement, dated March 11,
2009, between BioTime and Wisconsin Alumni Research Foundation.
^^^^
|
|
|
|
10.30
|
|
Employment
Agreement, dated October 10, 2007, between BioTime, Inc. and Robert
Peabody. ^^^^
|
|
|
|
10.31
|
|
Fifth
Amendment of Revolving Line of Credit Agreement, dated April 15,
2009.‡‡‡‡‡
|
|
|
|
10.32
|
|
Form
of Amendment of Revolving Credit Note. ‡‡‡‡‡
|
|
|
|
10.33
|
|
Fifth
Amendment of Security Agreement, dated April 15, 2009.
‡‡‡‡‡
|
|
|
|
10.34
|
|
Stock
and Warrant Purchase Agreement between BioTime, Inc. and George Karfunkel.
~~
|
|
|
|
10.35
|
|
Stock
and Warrant Purchase Agreement between BioTime, Inc. and Broadwood
Partners, L.P. ~~
|
|
|
|
10.36
|
|
Registration
Rights Agreement between BioTime, Inc., Broadwood Partners, L.P. and
George Karfunkel. ~~~
|
|
|
|
10.37
|
|
Co-Exclusive
OEM Supply Agreement, date July 7, 2009, between Embryome Sciences, Inc.
and Millipore Corporation (Portions of this exhibit have been omitted
pursuant to a request for confidential treatment). ~~~
|
|
|
|
10.38
|
|
Stock
Purchase Agreement between OncoCyte Corporation and George
Karfunkel.§
|
10.39
|
|
Registration
Rights Agreement between OncoCyte Corporation and George Karfunkel.
§
|
|
|
|
31
|
|
Rule
13a-14(a)/15d-14(a) Certification. §
|
|
|
|
32
|
|
Section
1350 Certification. §
|
|
|
|
+
|
|
Incorporated
by reference to Registration Statement on Form S-1, File Number 33-44549
filed with the Securities and Exchange Commission on December 18, 1991,
and Amendment No. 1 and Amendment No. 2 thereto filed with the Securities
and Exchange Commission on February 6, 1992 and March 7, 1992,
respectively.
|
|
|
|
#
|
|
Incorporated
by reference to Registration Statement on Form S-1, File Number 33-48717
and Post-Effective Amendment No. 1 thereto filed with the Securities and
Exchange Commission on June 22, 1992, and August 27, 1992,
respectively.
|
|
|
|
++
|
|
Incorporated
by reference to Registration Statement on Form S-2, File Number
333-109442, filed with the Securities and Exchange Commission on October
3, 2003, and Amendment No.1 thereto filed with the Securities and Exchange
Commission on November 13, 2003.
|
|
|
|
+++
|
|
Incorporated
by reference to Registration Statement on Form S-2, File Number
333-128083, filed with the Securities and Exchange Commission on September
2, 2005.
|
|
|
|
##
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed April 24,
1997.
|
|
|
|
^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
1999.
|
|
|
|
*
|
|
Incorporated
by reference to BioTime’s Form 10-K for the year ended December 31,
2001.
|
|
|
|
**
|
|
Incorporated
by reference to BioTime’s Form 10-K/A-1 for the year ended December 31,
2002.
|
|
|
|
‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed December 30,
2004.
|
|
|
|
‡‡
|
|
Incorporated
by reference to Post-Effective Amendment No. 3 to Registration Statement
on Form S-2 File Number 333-109442, filed with the Securities and Exchange
Commission on May 24, 2005.
|
|
|
|
‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed December 20,
2005.
|
|
|
|
††
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed January 13,
2006.
|
†††
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed March 30,
2006.
|
|
|
|
***
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2006.
|
|
|
|
****
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed January 9,
2008.
|
|
|
|
‡‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed March 10,
2008.
|
|
|
|
~
|
|
Incorporated
by reference to BioTime’s Form 8-K filed April 4, 2008.
|
|
|
|
++++
|
|
Incorporated
by reference to BioTime’s Form 10-KSB for the year ended December 31,
2007.
|
|
|
|
^^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2008.
|
|
|
|
^^^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended September 30,
2008.
|
|
|
|
^^^^
|
|
Incorporated
by reference to BioTime’s Form 10-K for the year ended December 31,
2008.
|
|
|
|
‡‡‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K filed April 17,
2009.
|
|
|
|
~~
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended March 31,
2009.
|
|
|
|
~~~
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2009.
|
|
|
|
§
|
|
Filed
herewith.
|
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the Registrant has
duly caused this report to be signed on its behalf by the undersigned, thereunto
duly authorized.
BIOTIME,
INC.
|
|
|
|
|
|
Date:
November 12, 2009
|
/s/ Michael D.
West
|
|
Michael D.
West
|
|
Chief Executive
Officer
|
|
|
|
|
Date:
November 12, 2009
|
/s/ Steven A.
Seinberg
|
|
Steven A.
Seinberg
|
|
Chief Financial
Officer
|
Exhibit
Numbers
|
|
Description
|
|
|
|
|
|
Articles
of Incorporation with all amendments.§
|
|
|
|
3.2
|
|
By-Laws,
As Amended.#
|
|
|
|
4.1
|
|
Specimen
of Common Share Certificate.+
|
|
|
|
4.2
|
|
Form
of Warrant Agreement between BioTime, Inc. and American Stock Transfer
& Trust Company++
|
|
|
|
4.3
|
|
Form
of Amendment to Warrant Agreement between BioTime, Inc. and American Stock
Transfer & Trust Company. +++
|
|
|
|
4.4
|
|
Form
of Warrant+++
|
|
|
|
4.5
|
|
Warrant
Agreement between BioTime, Inc., Broadwood Partners, L.P., and George
Karfunkel ~~
|
|
|
|
4.6
|
|
Form
of Warrant ~~
|
|
|
|
10.1
|
|
Intellectual
Property Agreement between BioTime, Inc. and Hal
Sternberg.+
|
|
|
|
10.2
|
|
Intellectual
Property Agreement between BioTime, Inc. and Harold
Waitz.+
|
|
|
|
10.3
|
|
Intellectual
Property Agreement between BioTime, Inc. and Judith
Segall.+
|
|
|
|
10.4
|
|
Intellectual
Property Agreement between BioTime, Inc. and Steven
Seinberg.*
|
|
|
|
10.5
|
|
Agreement
between CMSI and BioTime Officers Releasing Employment Agreements, Selling
Shares, and Transferring Non-Exclusive License.+
|
|
|
|
10.6
|
|
Agreement
for Trans Time, Inc. to Exchange CMSI Common Stock for BioTime, Inc.
Common Shares.+
|
|
|
|
|
|
2002
Stock Option Plan, as amended. §
|
|
|
|
10.8
|
|
Exclusive
License Agreement between Abbott Laboratories and BioTime,
Inc. (Portions of this exhibit have been omitted pursuant to a
request for confidential treatment).##
|
|
|
|
10.9
|
|
Modification
of Exclusive License Agreement between Abbott Laboratories and BioTime,
Inc. (Portions of this exhibit have been omitted pursuant to a request for
confidential treatment).^
|
10.10
|
|
Exclusive
License Agreement between BioTime, Inc. and CJ Corp.**
|
|
|
|
10.11
|
|
Hextend
and PentaLyte Collaboration Agreement between BioTime, Inc. and Summit
Pharmaceuticals International Corporation.‡
|
|
|
|
10.12
|
|
Lease
dated as of May 4, 2005 between BioTime, Inc. and Hollis R& D
Associates ‡‡
|
|
|
|
10.13
|
|
Addendum
to Hextend and PentaLyte Collaboration Agreement Between BioTime Inc. And
Summit Pharmaceuticals International Corporation‡‡‡
|
|
|
|
10.14
|
|
Amendment
to Exclusive License Agreement Between BioTime, Inc. and Hospira,
Inc.††
|
|
|
|
10.15
|
|
Hextend
and PentaLyte China License Agreement Between BioTime, Inc. and Summit
Pharmaceuticals International Corporation.†††
|
|
|
|
10.16
|
|
Employment
Agreement, dated October 10, 2007, between BioTime, Inc. and Michael D.
West.++++
|
|
|
|
10.17
|
|
Commercial
License and Option Agreement between BioTime and Wisconsin Alumni Research
Foundation.****
|
|
|
|
10.18
|
|
Form
of Amended and Restated Revolving Credit Note.‡‡‡‡
|
|
|
|
10.19
|
|
Third
Amended and Restated Revolving Line of Credit Agreement, March 31,
2008.~
|
|
|
|
10.20
|
|
Third
Amended and Restated Security Agreement, dated March 31,
2008.~
|
|
|
|
10.21
|
|
Sublease
Agreement between BioTime, Inc. and Avigen, Inc.++++
|
|
|
|
10.22
|
|
License,
Product Production, and Distribution Agreement, dated June 19, 2008, among
Lifeline Cell Technology, LLC, BioTime, Inc., and Embryome Sciences, Inc.
^^
|
|
|
|
10.23
|
|
License
Agreement, dated July 10, 2008, between Embryome Sciences, Inc. and
Advanced Cell Technology, Inc.
^^
|
10.24
|
|
License
Agreement, dated August 15, between Embryome Sciences, Inc. and Advanced
Cell Technology, Inc. ^^^
|
|
|
|
10.25
|
|
Sublicense
Agreement, dated August 15, between Embryome Sciences, Inc. and Advanced
Cell Technology, Inc. ^^^
|
|
|
|
10.26
|
|
Fourth
Amendment of Revolving Line of Credit Agreement.^^^
|
|
|
|
10.27
|
|
Fourth
Amendment of Security Agreement.^^^
|
|
|
|
10.28
|
|
Stem
Cell Agreement, dated February 23, 2009, between Embryome Sciences, Inc.
and Reproductive Genetics Institute. ^^^^
|
|
|
|
10.29
|
|
First
Amendment of Commercial License and Option Agreement, dated March 11,
2009, between BioTime and Wisconsin Alumni Research Foundation.
^^^^
|
|
|
|
10.30
|
|
Employment
Agreement, dated October 10, 2007, between BioTime, Inc. and Robert
Peabody. ^^^^
|
|
|
|
10.31
|
|
Fifth
Amendment of Revolving Line of Credit Agreement, dated April 15,
2009.‡‡‡‡‡
|
|
|
|
10.32
|
|
Form
of Amendment of Revolving Credit Note. ‡‡‡‡‡
|
|
|
|
10.33
|
|
Fifth
Amendment of Security Agreement, dated April 15, 2009.
‡‡‡‡‡
|
|
|
|
10.34
|
|
Stock
and Warrant Purchase Agreement between BioTime, Inc. and George Karfunkel.
~~
|
|
|
|
10.35
|
|
Stock
and Warrant Purchase Agreement between BioTime, Inc. and Broadwood
Partners, L.P. ~~
|
|
|
|
10.36
|
|
Registration
Rights Agreement between BioTime, Inc., Broadwood Partners, L.P. and
George Karfunkel. ~~~
|
|
|
|
10.37
|
|
Co-Exclusive
OEM Supply Agreement, date July 7, 2009, between Embryome Sciences, Inc.
and Millipore Corporation (Portions of this exhibit have been omitted
pursuant to a request for confidential treatment). ~~~
|
|
|
|
|
|
Stock
Purchase Agreement between OncoCyte Corporation and George
Karfunkel.§
|
|
|
|
|
|
Registration
Rights Agreement between OncoCyte Corporation and George Karfunkel.
§
|
|
|
Rule
13a-14(a)/15d-14(a) Certification. §
|
|
|
|
|
|
Section
1350 Certification. §
|
+
|
|
Incorporated
by reference to Registration Statement on Form S-1, File Number 33-44549
filed with the Securities and Exchange Commission on December 18, 1991,
and Amendment No. 1 and Amendment No. 2 thereto filed with the Securities
and Exchange Commission on February 6, 1992 and March 7, 1992,
respectively.
|
|
|
|
#
|
|
Incorporated
by reference to Registration Statement on Form S-1, File Number 33-48717
and Post-Effective Amendment No. 1 thereto filed with the Securities and
Exchange Commission on June 22, 1992, and August 27, 1992,
respectively.
|
|
|
|
++
|
|
Incorporated
by reference to Registration Statement on Form S-2, File Number
333-109442, filed with the Securities and Exchange Commission on October
3, 2003, and Amendment No.1 thereto filed with the Securities and Exchange
Commission on November 13, 2003.
|
|
|
|
+++
|
|
Incorporated
by reference to Registration Statement on Form S-2, File Number
333-128083, filed with the Securities and Exchange Commission on September
2, 2005.
|
|
|
|
##
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed April 24,
1997.
|
|
|
|
^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
1999.
|
|
|
|
*
|
|
Incorporated
by reference to BioTime’s Form 10-K for the year ended December 31,
2001.
|
|
|
|
**
|
|
Incorporated
by reference to BioTime’s Form 10-K/A-1 for the year ended December 31,
2002.
|
|
|
|
‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed December 30,
2004.
|
|
|
|
‡‡
|
|
Incorporated
by reference to Post-Effective Amendment No. 3 to Registration Statement
on Form S-2 File Number 333-109442, filed with the Securities and Exchange
Commission on May 24, 2005.
|
|
|
|
‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed December 20,
2005.
|
|
|
|
††
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed January 13,
2006.
|
|
|
|
†††
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed March 30,
2006.
|
***
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2006.
|
|
|
|
****
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed January 9,
2008.
|
|
|
|
‡‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K, filed March 10,
2008.
|
|
|
|
~
|
|
Incorporated
by reference to BioTime’s Form 8-K filed April 4, 2008.
|
|
|
|
++++
|
|
Incorporated
by reference to BioTime’s Form 10-KSB for the year ended December 31,
2007.
|
|
|
|
^^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2008.
|
|
|
|
^^^
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended September 30,
2008.
|
|
|
|
^^^^
|
|
Incorporated
by reference to BioTime’s Form 10-K for the year ended December 31,
2008.
|
|
|
|
‡‡‡‡‡
|
|
Incorporated
by reference to BioTime’s Form 8-K filed April 17,
2009.
|
|
|
|
~~
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended March 31,
2009.
|
|
|
|
~~~
|
|
Incorporated
by reference to BioTime’s Form 10-Q for the quarter ended June 30,
2009.
|
|
|
|
§
|
|
Filed
herewith.
|
33
ex3_1.htm
|
1516389
ENDORSED
FILED
in
the office of the Secretary of State
of
the State of California
NOV
30 1990
MARCH
FONG EU, Secretary of State
|
ARTICLES
OF INCORPORATION
OF
BIOTIME,
INC
I
The name
of the corporation is BIOTIME, INC.
II
The
purpose of this corporation is to engage in any lawful act or activity for which
a corporation may be organized under the general Corporation Law of California
other than the banking business, the trust company business or the practice of a
profession permitted to be incorporated by the California Corporations
Code.
III
NUMBER OF
DIRECTORS
The
authorized number of directors shall be no less than seven nor more than
thirteen as
set by resolution of the Board of Directors. The initial number of directors
shall be seven.
IV
The name
and address in this state of the corporation's initial agent for service of
process is:
|
Ronald
S. Barkin
3050
Shattuck Avenue
Berkeley,
CA 97404
|
V
This
corporation is authorized to issue only one class of shares of stock which shall
be designated common stock. The total number of shares it is authorized to issue
is ten million (10,000,000).
VI
NO
PREFERENCES, PRIVILEGES, RESTRICTIONS
No
distinctions shall exist between the shares of the corporation of the holders
thereof.
IN
WITNESS WHEREOF, the undersigned, who are the incorporators of this corporation
have executed these Articles of Incorporation on November 30, 1990.
|
/s/ Ronald S. Barkin
|
|
RONALD
S. BARKIN, Incorporator
|
AMENDED
ARTICLES OF INCORPORATION
OF
BIOTIME,
INC.
Paul
Segall and Judith Segall certify that:
1.
They are the President and the Secretary, respectively, of BioTime, Inc.,
a California Corporation.
2.
The Articles of Incorporation of this corporation are amended to read in full as
follows:
"ONE: The
name of this corporation is BioTime, Inc.
TWO: The
purpose of the corporation is to engage in any lawful act or activity for which
a corporation may be organized under the General Corporation Law of California
other than the banking business, the trust company business, or the practice of
a profession permitted to be incorporated by the California Corporations
Code.
THREE:
The corporation is authorized to issue two classes of shares, which shall be
designated "Common Shares" and "Preferred Shares". The number of Common Shares
which the corporation is authorized to issue is 5,000,000 and the number of
Preferred Shares which the corporation is authorized to issue is 1,000,000. The
Preferred Shares may be issued in one or more series as the board of directors
may by resolution determine. The board of directors is authorized to fix the
number of shares of any series of Preferred Shares and to determine or alter the
rights, preferences, privileges, and restrictions granted to or imposed on the
shares of Preferred Shares as a class, or upon any wholly unissued series of any
Preferred Shares. The board of directors may, by resolution, increase or
decrease (but not below the number of shares of such series then outstanding)
the number of shares of any series of Preferred Shares subsequent to the issue
of shares of that series. Upon the amendment of this article to read as herein
set forth, each outstanding share of common stock is converted into or
reconstituted as 0.1667 Common Share.
FOUR: The
liability of the directors of the corporation for monetary damages shall be
eliminated to the fullest extent permissible under California law. The
corporation is authorized to indemnify "agents", as such term is defined in
Section 317 of the California Corporations Code, to the fullest extent
permissible under California law."
3.
The foregoing amendment of articles of incorporation has been duly approved by
the board of directors.
4.
The foregoing amendment of articles of incorporation has been duly approved by
the required vote of shareholders in accordance with Section 902 of the
Corporations Code. The total number of outstanding shares of the corporation is
5,351,672. The number of shares voting in favor of the amendment equaled or
exceeded the vote required. The percentage vote required was more than
50%.
We
further declare under penalty of perjury under the laws of the State of
California that the matters set forth in this amendment are true and correct of
our own knowledge.
Date:
July 15, 1991
|
/s/ Paul Segall
|
|
Paul
Segall, President
|
|
|
|
|
|
|
|
|
|
/s/ Judith Segall
|
|
Judith
Segall, Secretary
|
|
A494281
ENDORSED
FILED
in
the office of the Secretary of State
of
the State of California
JUL
20 1997
/s/
Bill Jones
BILL
JONES, Secretary of State
|
CERTIFICATE
OF AMENDMENT
OF
ARTICLES
OF INCORPORATION
Paul E.
Segall and Judith Segall certify that:
1. They
are the President and Secretary, respectively, of BioTime, Inc., a California
corporation.
2. The
sentence of Article THREE of the Articles of Incorporation that now reads "The
number of Common Shares which the Corporation is authorized to issue is
5,000,000 and the number of Preferred Shares which the Corporation is authorized
to issue is 1,000,000" is amended to read as follows:
"The
number of Common Shares which the Corporation is authorized to issue is
25,000,000 and the number of Preferred Shares which the Corporation is
authorized to issue is 1,000,000."
3. The
foregoing amendment of Articles of Incorporation has been duly approved by the
board of directors.
4. The
foregoing amendment of Articles of Incorporation has been duly approved by the
required vote of shareholders in accordance with section 902 of the Corporations
Code. The total number of outstanding Common Shares of the corporation is
3,203,193. There are no Preferred Shares outstanding. The number of Common
Shares voting in favor of the amendment equaled or exceeded the vote required.
The percentage vote required was more than 50%.
We
further declare under penalty of perjury under the laws of the State of
California that the matters set forth in this certificate are true and correct
of our own knowledge.
Executed
at Berkeley, California on June 20, 1997.
|
/s/ Paul Segall
|
|
Paul
E. Segall, President
|
|
|
|
|
|
|
|
|
|
/s/ Judith Segall
|
|
Judith
Segall, Secretary
|
|
A0510119
ENDORSED
- FILED
in
the office of the Secretary of State
of
the State of California
JUL
18 1998
BILL
JONES, Secretary of State
|
CERTIFICATE
OF AMENDMENT
OF
ARTICLES
OF INCORPORATION
Ronald S.
Barkin and Judith Segall certify that:
1. They
are the President and Secretary, respectively, of BioTime, Inc., a California
corporation.
2. The
sentence of Article THREE of the Articles of Incorporation that now reads "The
number of Common Shares which the Corporation is authorized to issue is
25,000,000 and the number of Preferred Shares which the Corporation is
authorized to issue is 1,000,000" is amended to read as follows:
"The
number of Common Shares which the Corporation is authorized to issue is
40,000,000 and the number of Preferred Shares which the Corporation is
authorized to issue is 1,000,000."
3. The
foregoing amendment of Articles of Incorporation has been duly approved by the
board of directors.
4. The
foregoing amendment of Articles of Incorporation has been duly approved by the
required vote of shareholders in accordance with section 902 of the Corporations
Code. The total number of outstanding Common Shares of the corporation entitled
to vote with respect to the amendment was 9,935,579. There are no Preferred
Shares outstanding. The number of Common Shares voting in favor of the amendment
equaled or exceeded the vote required. The percentage vote required was more
than 50%.
We
further declare under penalty of perjury under the laws of the State of
California that the matters set forth in this certificate are true and correct
of our own knowledge.
Executed
at Berkeley, California on June 1, 1998.
|
/s/ Ronald S. Barkin
|
|
Ronald
S. Barkin, President
|
|
|
|
|
|
|
|
|
|
/s/ Judith Segall
|
|
Judith
Segall, Secretary
|
|
|
|
A0648585
FILED
in
the office of the Secretary of State
of
the State of California
JUL
27 2006
|
CERTIFICATE
OF AMENDMENT
OF
ARTICLES
OF INCORPORATION
Hal
Sternberg and Judith Segall certify that:
1.
They are the Vice-President and Secretary, respectively, of BioTime, Inc., a
California corporation.
2.
The second sentence of Article THREE of the Articles of Incorporation of the
corporation is amended to read as follows:
"The
number of Common Shares which the corporation is authorized to issue is
50,000,000, and the number of Preferred Shares which the corporation is
authorized to issue is 1,000,000."
3.
The foregoing amendment of Articles of Incorporation has been duly approved by
the board of directors.
4.
The foregoing amendment of Articles of Incorporation has been duly approved by
the required vote of shareholders in accordance with section 902 of the
Corporations Code. The total number of outstanding shares of the corporation
entitled to vote with respect to the amendment was 22,574,374. The number of
shares voting in favor of the amendment equaled or exceeded the vote required.
The percentage vote required was more than 50%.
We
further declare under penalty of perjury under the laws of the State of
California that the matters set forth in this certificate are true and correct
of our own knowledge.
Executed
at Emeryville, California on July 25, 2006.
|
/s/ Hal Sternberg
|
|
Hal
Sternberg, Vice President
|
|
|
|
|
|
/s/ Judith Segall
|
|
Judith
Segall, Secretary
|
|
A0697146
ENDORSED
- FILED
in
the office of the Secretary of State
of
the State of California
OCT 19
2009
|
CERTIFICATE
OF AMENDMENT
OF
ARTICLES
OF INCORPORATION
Michael
D. West and Judith Segall certify that:
1.
They are the President and Secretary, respectively, of BioTime, Inc., a
California corporation.
2.
Article THREE of the Articles of Incorporation of the corporation is amended to
read as follows:
THREE:
The corporation is authorized to issue two classes of shares, which shall be
designated "Common Shares" and "Preferred Shares". The number of Common Shares
which the corporation is authorized to issue is 75,000,000, and the number of
Preferred Shares which the corporation is authorized to issue is 1,000,000. The
Preferred Shares may be issued in one or more series as the board of directors
may by resolution designate. The board of directors is authorized to fix the
number of shares of any series of Preferred Shares and to determine or alter the
rights, preferences, privileges, and restrictions granted to or imposed upon the
Preferred Shares as a class, or upon any wholly unissued series of Preferred
Shares. The board of directors may, by resolution, increase or decrease (but not
below the number of shares of such series then outstanding) the number of shares
of any series of Preferred Shares subsequent to the issue of shares of that
series.
3.
The foregoing amendment of Articles of Incorporation has been duly approved by
the board of directors.
4.
The foregoing amendment of Articles of Incorporation has been duly
approved by the required vote of shareholders in accordance with section 902 of
the Corporations Code. The total number of outstanding Common Shares of the
corporation entitled to vote with respect to the amendment was 32,614,563. The
number of Common Shares voting in favor of the amendment equaled or exceeded the
vote required. The percentage vote required was more than 50%. There are no
Preferred Shares of the corporation issued and outstanding.
We
further declare under penalty of perjury under the laws of the State of
California that the matters set forth in this certificate are true and correct
of our own knowledge.
Executed
at Alameda, California on October 16, 2009.
|
/s/ Michael D. West
|
|
Michael
D. West, President
|
|
|
|
|
|
/s/ Judith Segall
|
|
Judith
Segall, Secretary
|
ex10_7.htm
Exhibit
10.7
BIOTIME,
INC.
2002
STOCK OPTION PLAN
GENERAL
1.
PURPOSE
This
BioTime, Inc. Stock Option Plan (the “Plan”) is intended to increase incentive
and to encourage stock ownership on the part of selected key officers,
directors, employees, consultants, professionals, and other individuals whose
efforts may aid BioTime, Inc., a California corporation (the “Company”) or any
other corporations that are or which may become subsidiaries or a parent of the
Company. Except where the context obviously requires otherwise, as
used in this Plan, the term “Company” includes BioTime, Inc., a California
corporation, and any corporation that is or becomes a parent or subsidiary, as
defined in Section 425 of the Internal Revenue Code of 1986, as amended (the
“Code”), of BioTime, Inc. It is intended that certain options granted
pursuant to the Plan shall constitute incentive stock options within the meaning
of Section 422(b) of the Code and that certain other options granted pursuant to
the Plan shall not constitute incentive stock options (“nonqualified stock
options”).
2.
ADMINISTRATION
The Plan
shall be administered by the Company’s Board of Directors (the “Board”) or, in
the discretion of the Board, by a committee (the “Committee”) of not less than
two members of the Board. The Committee’s interpretation and
construction of any term or provision of the Plan or of any option granted under
the Plan shall be final, unless otherwise determined by the Board, in which
event such determination by the Board shall be final. The Committee
may from time to time adopt rules and regulations for carrying out this Plan
and, subject to the provisions of this Plan, may prescribe the form or forms of
the instruments evidencing any option granted under this Plan. No
member of the Committee shall be liable for any action or determination made in
good faith with respect to the Plan or any option granted, or with respect to
any shares sold under any restricted stock purchase agreement, under the
Plan.
Subject
to the provisions of this Plan, the Board or the Committee shall have full and
final authority in its discretion to select the eligible persons to whom options
are granted or shares are sold under restricted stock purchase agreements, to
grant such options and to sell shares as provided in this Plan, to determine the
number of shares to be subject to options or sold pursuant to restricted stock
purchase agreements, to determine the exercise prices of options or purchase
prices of shares under restricted stock purchase agreements, the terms of
exercise of options, expiration dates of options, and other pertinent terms and
provisions of options and restricted stock purchase agreements. The
Board may delegate to the Committee the power to make all determinations with
respect to the Plan, or may delegate to the Committee only certain aspects of
Plan administration, such as selecting the eligible persons to whom options will
be granted, or decisions concerning the timing, pricing, and amount of a grant
or award of options or sale of shares under restricted stock purchase
agreements.
3.
ELIGIBILITY
Subject
to Section 2 of this Article I, the persons who shall be eligible to receive
options or to purchase shares under restricted stock purchase
agreements under the Plan shall be such officers, employees, directors,
consultants, professionals, and independent contractors of the Company as the
Board of Directors or the Committee may select. Eligible persons who
are not also salaried employees of the Company shall be eligible to receive
nonqualified stock options (but such persons shall not be eligible to receive
incentive stock options).
4.
SHARES OF STOCK SUBJECT TO
THE PLAN
The
shares that may be issued under the Plan shall be authorized and unissued or
reacquired common shares, no par value, of the Company (the
“Shares”). The aggregate number of Shares which may be issued under
the Plan shall not exceed 1,000,000, unless an adjustment is required in
accordance with Article III.
5.
AMENDMENT OF THE
PLAN
The Board
may, insofar as permitted by law, from time to time, suspend or discontinue the
Plan or revise or amend it in any respect whatsoever, except that no such
amendment shall alter or impair or diminish any rights or obligations under any
option theretofore granted or under any restricted stock purchase agreement
executed under the Plan, without the consent of the person to whom such option
was granted or Shares were sold, except as permitted under Section 8 of this
Article I. Without further shareholder approval, no such
amendment shall increase the number of shares subject to the Plan (except as
authorized by Article III), change the designation in Section 3 of Article I of
the class of persons eligible to receive options or purchase Shares under the
Plan, extend the term during which options may be exercised, or extend the final
date upon which options under the Plan may be granted or Shares may be sold
under restricted stock purchase agreements.
6.
APPROVAL OF
SHAREHOLDERS
All
options granted under the Plan before the Plan is approved by affirmative vote
of the holders of a majority of the voting shares of the Company present and
eligible to vote at the next meeting of shareholders of the Company, or any
adjournment thereof, shall be subject to such approval. No option
granted hereunder may become exercisable unless and until such approval is
obtained.
7.
TERM OF
PLAN
Options
may be granted and Shares may be sold under restricted stock purchase agreements
under the Plan until September 10, 2012, the date of termination of the
Plan. Notwithstanding the foregoing, each option granted under the
Plan shall remain in effect until such option has been exercised or terminated
in accordance with its terms and the terms of the Plan.
8.
LISTING, REGISTRATION,
QUALIFICATION, AND CONSENTS
All
options granted under the Plan shall be subject to the requirement that, if at
any time the Board or the Committee shall determine, in its discretion, that the
listing, registration or qualification of the shares subject to options granted
under the Plan, upon any securities exchange or under any state or federal law,
or the consent or approval of any government regulatory body, is necessary or
desirable as a condition of, or in connection with, the granting of such option
or the issuance, if any, or purchase of shares in connection therewith, such
option may not be exercised in whole or in part unless such listing,
registration, qualification, consent or approval shall have been effected or
obtained free of any conditions not acceptable to the Board or the
Committee. Furthermore, if the Board or the Committee determines that
any amendment to any option (including, but not limited to, an increase in the
exercise price) is necessary or desirable in connection with the registration or
qualification of any of its shares under any state securities or “blue sky” law,
then the Board or the Committee shall have the unilateral right to make such
changes without the consent of the optionee.
9.
NONASSIGNABILITY
Nonqualified
options shall be transferable (i) by will, by the laws of descent and
distribution, by instrument to an inter vivos or testamentary trust in which the
nonqualified options are to be passed to beneficiaries upon the death of the
optionee or (ii) to the extent and in the manner authorized by the Board or
Committee by gift to members of the optionee’s immediate
family. Immediate family means a transferee as permitted by Rule
260.140.41 of Title 10 of the California Code of Regulations which includes any
child, stepchild, grandchild, parent, stepparent, grandparent, spouse, sibling,
mother-in-law, father-in-law, son-in-law, daughter-in-law, brother-in-law, or
sister-in-law and shall also include adoptive
relationships. Incentive stock options may not be sold, pledged,
assigned, hypothecated, transferred, or disposed of in any manner other than by
will or by the laws of descent or distribution and may be exercised, during the
lifetime of the optionee, only by the optionee. Notwithstanding
the preceding two sentences, in conjunction with the exercise of an option, and
for the purpose of obtaining financing for such exercise, the option holder may
arrange for a securities broker/dealer to exercise an option on the option
holder’s behalf, to the extent necessary to obtain funds required to pay the
exercise price of the option.
10.
WITHHOLDING
TAXES
Whenever
Shares are to be issued upon the exercise of any option under the Plan or under
any restricted stock purchase agreement, the Company shall have the right to
require the optionee or purchaser to remit to the Company an amount sufficient
to satisfy federal, state, and local withholding tax requirements prior to the
delivery of any certificate or certificates for such Shares.
11.
DEFINITION OF “FAIR MARKET
VALUE”
For the
purposes of this Plan, the term “fair market value,” when used in reference to
the date of grant of an option or the date of surrender of Shares in payment for
the purchase of Shares pursuant to the exercise of any option, as the case may
be, shall mean the amount determined by the Board or the Committee as
follows:
(a)
If the Shares are listed or have
unlisted trading privileges on a national securities exchange (which for the
purposes of this Plan shall also include the Nasdaq Stock Market National
Market), the Shares shall be valued at their last sale price on the principal
national securities exchange (measured by volume of transactions in such Shares)
on which such securities shall have traded, or, if available, such sales price
as reported on the composite tape, on the last trading day immediately preceding
the date of grant or surrender.
(b)
If the Shares are described in either
subparagraph (a) or (b) above but were not traded on the last trading day
immediately preceding the date of grant or surrender, or if prices of the Shares
are quoted in the National Association of Securities Dealers, Inc., Automated
Quotation system (but which not the National Market System), or if
prices of the Shares are published by the National Quotation Bureau, Inc., then
the Shares shall be valued at the average between the last bid and the last
asked prices reported in the Wall Street Journal or published by the National
Quotation Bureau within the 30 days prior to the date of grant or
surrender.
(c)
If the Shares are not described in and valued
under subparagraphs (a) and (b) above, then the Shares shall be valued by the
Board or the Committee, in its sole judgement, in good faith.
ARTICLE
II
STOCK
OPTIONS
1.
AWARD OF STOCK
OPTIONS
Awards of
stock options may be made under the Plan under all the terms and conditions
contained herein. However, in the case of incentive stock options,
the aggregate fair market value (determined as of the date of grant of the
option) of the Shares with respect to which incentive stock options are
exercisable for the first time by such officer or key employee during any
calendar year (under all incentive stock option plans of the Company) shall not
exceed $100,000. The date on which any option is granted shall be the
date of the Board’s or the Committee’s authorization of such grant or such later
date as may be determined by the Board or the Committee at the time such grant
is authorized.
2.
TERM OF OPTIONS AND EFFECT
OF TERMINATION
Notwithstanding
any other provision of the Plan, an option shall not be exercisable after the
expiration of ten (10) years from the date of its grant. In addition,
notwithstanding any other provision of the Plan, no incentive stock option
granted under the Plan to a person who, at the time such option is granted, owns
shares possessing more than 10% of the total combined voting power of all
classes of shares of the Company or of any parent or subsidiary corporation,
shall be exercisable after the expiration of five (5) years from the date of its
grant.
In the
event that any outstanding option under the Plan expires by reason of lapse of
time or otherwise is terminated or canceled for any reason, then the Shares
subject to any such option which have not been issued pursuant to the exercise
of the option shall again become available in the pool of Shares for which
options may be granted under the Plan.
3.
CANCELLATION OF AND
SUBSTITUTION FOR OPTIONS
The
Company shall have the right to cancel any option at any time before it
otherwise would have expired by its terms and to grant to the same optionee in
substitution therefor a new stock option stating an option price which is lower
(but not higher) than the option price stated in the canceled
option. Any such substituted option shall contain all the terms and
conditions of the canceled option provided, however, that notwithstanding
Section 2 of Article II, such substituted option shall not be exercisable after
the expiration of ten (10) years from the date of grant of the canceled
option.
4.
TERMS AND
CONDITIONS OF OPTIONS
Options
granted pursuant to the Plan shall be evidenced by agreements in such form as
the Board or the Committee shall from time to time determine, which agreements
shall comply with the following terms and conditions.
(a)
Number of Shares and Type of
Option
Each
option agreement shall state the number of Shares for which the option is
exercisable and whether the option is intended to be an incentive stock option
or a nonqualified stock option.
(b)
Option
Price
Each
option agreement shall state the exercise price per share or the method by which
such price shall be computed. The exercise price per share shall be
determined by the Board or the Committee at the date such option is
granted. In the case of a nonqualified option, the exercise price may
be not less than 85% of the fair market value of the Shares on the date such
option is granted. In the case of an incentive stock option, the
exercise price shall be not less than 100% of the fair market value of the
Shares on the date such option is granted. Notwithstanding the
foregoing, the exercise price per share of a option granted to a person who, on
the date of such grant and in accordance with Section 425(d) of the Code, owns
shares possessing more than 10% of the total combined voting power of all
classes of shares of the Company or of any parent or subsidiary corporation,
shall be not less than 110% of the fair market value of the Shares on the date
that the option is granted.
(c)
Medium and Time of
Payment
The
exercise price shall be payable upon the exercise of an option in the lawful
currency of the United States of America or, in the discretion of the Board or
the Committee, in Shares or in a combination of such currency and such
Shares. Upon receipt of payment, the Company shall deliver to the
optionee (or person entitled to exercise the option) a certificate or
certificates for the Shares purchased through such exercise.
(d)
Exercise of
Options
Options
granted under the Plan shall vest, and thereby become exercisable, at the time
or times, or upon the happening of the events or circumstances, determined by
the Board or the Committee. All options granted to employees who are
not officers, directors, or consultants shall vest at a rate not less than 20%
per year over 5 years from the date of sale. Options granted to
officers, directors, and consultants may vest at any time or from time to time
upon the satisfaction of reasonable conditions to vesting determined by the
Board or Committee. Without limiting the other events and
circumstances upon which vesting may be determined, the Board or Committee may
make vesting conditioned upon continued employment by the
Company. The terms under which options shall vest shall be stated in
each option agreement. The Board or the Committee may, in its
discretion, accelerate (but not delay or postpone) the time or times at which an
option vests.
To the
extent that an option has become vested (except as provided in Article III), and
subject to the foregoing restrictions, it may be exercised in whole or in such
lesser amount as may be authorized by the option agreement. If
exercised in part, the unexercised portion of an option shall continue to be
held by the optionee and may thereafter be exercised as herein
provided.
(e)
Termination of Employment
Except By Disability or Death
In the
event that an optionee who is an employee of the Company shall cease to be
employed by the Company for any reason other than his or her death or
disability, his or her option shall terminate on the date (3) months after the
date that he ceases to be an employee of the Company. The Committee
or the Board may waive the provisions of this Subsection 4(e) at the date of
grant of an option or at a later date.
(f)
Disability of
Optionee
If an
optionee who is an employee of the Company shall cease to be employed by the
Company by reason of his or her becoming disabled, such option shall terminate
on the date one (1) year after cessation of employment due to such
disability. “Disability” means that an employee is unable to carry
out the responsibilities and functions of the position held by the employee by
reason of any medically determinable physical or mental
impairment. The Committee or the Board may waive the provisions of
this Subsection 4(f) at the time of grant of an option or at a later date if the
option is not an incentive stock option.
(g)
Death of Optionee and
Transfer of Option
If an
optionee should die while in the employ of the Company, or within the
three-month period after termination of his or her employment with the Company
during which he or she is permitted to exercise an option in accordance with
Subsection 4(f) of this Article II, such option shall terminate on the date one
(1) year after the optionee’s death. During such one-year period,
such option may be exercised by the executors or administrators of the
optionee’s estate or by any person or persons who shall have acquired the option
directly from the optionee by his or her will or the applicable law of descent
and distribution. During such one year period, such option may be
exercised with respect to the number of Shares for which the deceased optionee
would have been entitled to exercise it at the time of his or her
death. The Committee or the Board may waive the provisions of this
Subsection 4(g) at the date of grant of an option or at a later date if the
option is not an incentive stock option.
ARTICLE
III
RECAPITALIZATIONS AND
REORGANIZATIONS
The
number of Shares covered by the Plan, and the number of Shares and price per
share of each outstanding option, shall be proportionately adjusted for any
increase or decrease in the number of issued and outstanding Shares resulting
from a subdivision or consolidation of Shares or the payment of a stock
dividend, or any other increase or decrease in the number of issued and
outstanding Shares effected without receipt of consideration by the
Company.
Upon the
dissolution or liquidation of the Company, or upon a reorganization, merger or
consolidation of the Company as a result of which the outstanding securities of
the class then subject to options hereunder are changed into or exchanged for
cash or property or securities not of the Company’s issue, or upon a sale of
substantially all the property of the Company to, or the acquisition of shares
representing more than eighty percent (80%) of the voting power of the shares of
the Company then outstanding by, another corporation or person, the Plan shall
terminate, and all options theretofore granted hereunder shall terminate, unless
provision can be made in writing in connection with such transaction for the
continuance of the Plan and/or for the assumption of options theretofore
granted, or the substitution for such options of options covering the shares of
a successor corporation, or a parent or a subsidiary thereof, with appropriate
adjustments as to the number and kind of shares and prices, in which event the
Plan and options theretofore granted shall continue in the manner and under the
terms so provided.
To the
extent that the foregoing adjustments relate to shares or securities of the
Company, such adjustments shall be made by the Board, whose determination in
that respect shall be final, binding and conclusive.
The grant
of an option pursuant to the Plan shall not affect in any way the right or power
of the Company to make adjustments, reclassifications, reorganizations or
changes or its capital or business structure or to merge or to consolidate or to
dissolve, liquidate or sell, or transfer all or any part of its business or
assets.
ARTICLE
IV
SALE OF RESTRICTED STOCK IN
LIEU OF GRANT OF OPTIONS
1.
RESTRICTED
STOCK
(a)
Number of
Shares
Each
restricted stock purchase agreement shall state the number of Shares sold under
such agreement.
(b)
Purchase
Price
Each
restricted stock purchase agreement shall state the purchase price per Share or
the method by which such price shall be computed. The Purchase price
per Share shall be determined by the Board or the Committee at the date the sale
of the Shares is approved (the “Approval Date”); provided that the purchase
price per Share may be not less than 85% of the fair market value per Share on
the Approval Date and that if the restricted shares are sold to an individual
who owns shares representing more than ten percent of the voting power of all
classes of shares of the Company (or any parent or subsidiary of the Company),
the purchase price per Share may not be less than 100% of the fair market value
per Share on the Approval Date.
(c)
Medium and Time of
Payment
The
purchase price shall be payable at the time the restricted stock purchase
agreement is executed by the eligible person. Payment shall be made
in the lawful currency of the United States of America or, in the discretion of
the Board or the Committee, by delivery of a promissory note payable to the
Company in such lawful currency. Upon receipt of payment, the Company
shall deliver to the eligible person a certificate or certificates for the
Shares purchased.
(d)
Repurchase
Option
Each
restricted stock purchase agreement shall provide that the Company shall have
the option to repurchase the Shares sold under such agreement in the event the
purchaser ceases to be a full time employee of the Company prior to the vesting
of such Shares, or if any other condition to the vesting of the Shares stated in
the restricted stock purchase agreement is not met (the “Repurchase
Option”). The Repurchase Option may be exercised by the Company
during such period as specified in the applicable restricted stock purchase
agreement. The price at which the Company may repurchase the Shares
upon the exercise of the Repurchase Option shall be the price at which the
Shares were sold to the eligible person, or such greater price as provided in
the applicable restricted stock purchase agreement approved by the Board or the
Committee. If the purchaser of Shares under a restricted stock
purchase agreement has delivered a promissory note as payment of all or part of
the purchase price of his or her Shares, the Company may cancel or reduce the
principal balance and interest accrued on that promissory note as payment of all
or part of the repurchase price upon exercise of the Repurchase
Option.
(e)
Vesting of
Shares. Shares sold pursuant to a restricted stock
purchase agreement shall vest, and thereby cease to be subject to the Repurchase
Option, at the time or times, or upon the happening of the events or
circumstances, determined by the Board or the Committee. All Shares
sold to employees who are not officers, directors, or consultants shall vest at
a rate not less than 20% per year over 5 years from the date of
sale. Shares sold to officers, directors, and consultants may vest at
any time or from time to time upon the satisfaction of reasonable conditions to
vesting determined by the Board or Committee. Without limiting the
other events and circumstances upon which vesting may be determined, the Board
or Committee may make vesting conditioned upon continued employment by the
Company. The terms under which Shares shall vest shall be stated in
the restricted stock purchase agreement. The Board or the Committee
may, in its discretion, accelerate (but not delay or postpone) the time or times
at which Shares vest under a restricted stock purchase agreement.
2.
ESCROW OF UNVESTED
SHARES.
The
Company may require that all Shares sold under a restricted stock purchase
agreement be held in escrow, on terms satisfactory to the Company, until such
Shares have vested and have been paid for in full (including the payment of any
amount due on any promissory note delivered by the purchaser and secured by such
Shares).
3.
LEGEND ON STOCK
CERTIFICATES.
Shares
issued under a restricted stock purchase agreement shall include, in addition to
any other legends as may be required by law or by the Board or Committee, a
legend to the following effect:
THESE
SHARES MAY BE TRANSFERRED ONLY IN ACCORDANCE WITH THE TERMS OF AN AGREEMENT
BETWEEN THE COMPANY AND THE SHAREHOLDER, A COPY OF WHICH IS ON FILE WITH THE
SECRETARY OF THE COMPANY.
ARTICLE V
MISCELLANEOUS
PROVISIONS
1.
RIGHTS AS A
STOCKHOLDER
An
optionee or a transferee of an option shall have no rights as a shareholder with
respect to any Shares covered by an option until the date of the receipt of
payment (including any amounts required by the Company pursuant to Section 10 of
Article I) by the Company. No adjustment shall be made as to any
option for dividends (ordinary or extraordinary, whether in cash, securities or
other property) or distributions or other rights for which the record date is
prior to such date, except as provided in Article III.
2.
MODIFICATION, EXTENSION AND
RENEWAL OF OPTIONS AND RESTRICTED STOCK PURCHASE AGREEMENTS
Subject
to the terms and conditions and within the limitations of the Plan, the Board or
the Committee may modify, extend, renew, or cancel outstanding options granted
under the Plan and restricted stock purchase
agreements. Notwithstanding the foregoing, however, no modification
of an option or restricted stock purchase agreement shall, without the consent
of the optionee or purchaser, impair or diminish any rights or obligations under
any option theretofore granted o restricted stock purchase agreement executed
under the Plan, except as provided in Section 8 of Article I. For
purposes of the preceding sentence, the right of the Company pursuant to Section
3 of Article II to cancel any outstanding option and to issue in place of such
canceled option a substituted option stating a lower option price shall not be
construed as impairing or diminishing an optionee’s rights or
obligations.
3.
OTHER
PROVISIONS
The
option agreements and restricted stock purchase agreements authorized under the
Plan shall contain such other provisions, including, without limitation,
restrictions upon the exercise of the option or purchase of Shares, or
restrictions required by any applicable securities laws, as the Board or the
Committee shall deem advisable.
4.
APPLICATION OF
FUNDS
The
proceeds received by the Company from the sale of Shares pursuant to the
exercise of options or under restricted stock purchase agreements will be used
for general corporate purposes.
5.
NO OBLIGATION TO EXERCISE
OPTION
The
granting of an option shall impose no obligation upon the optionee or a
transferee of the option to exercise such option.
6.
FINANCIAL
ASSISTANCE
Except as
may be prohibited by law, the Company is vested with authority under this Plan
to assist any employee to whom an option is granted or to whom Shares are sold
pursuant to a restricted stock purchase agreement hereunder (including any
director or officer of the Company or any of its subsidiaries who is also an
employee) in the payment of the purchase price payable on exercise of that
option or under that restricted stock purchase agreement, by lending the amount
of such purchase price (including accepting a promissory note executed by the
employee as consideration for the sale of the Shares at the time the Shares are
issued) to such employee on such terms and at such rates of interest and upon
such security (or unsecured) as shall have been authorized by or under authority
of the Board or the Committee.
7.
FINANCIAL
REPORTS.
The
Company shall deliver to each grantee of an option a balance sheet of the
Company as at the end of its most recently completed fiscal year, and an income
statement of the Company as of the end of such fiscal year. Such
financial statements shall be delivered no less frequently than annually;
provided, that such financial statements need not be delivered to any employee
whose duties as an employee assure them access to such financial
information.
AMENDMENT
TO
BIOTIME,
INC.
2002
STOCK OPTION PLAN
Effective
December 10, 2004, Article I, Section 4 is amended to read as
follows:
4.
SHARES OF STOCK SUBJECT TO
THE PLAN
The
shares that may be issued under the Plan shall be authorized and unissued or
reacquired common shares, no par value, of the Company (the
“Shares”). The aggregate number of Shares which may be issued under
the Plan shall not exceed 2,000,000, unless an adjustment is required in
accordance with Article III.
2007
AMENDMENT TO
BIOTIME,
INC.
2002
STOCK OPTION PLAN
Effective
October 15, 2009, Article I, Section 4 is amended to read as
follows:
4.
SHARES OF STOCK SUBJECT TO
THE PLAN
The
shares that may be issued under the Plan shall be authorized and unissued or
reacquired common shares, no par value, of the Company (the
“Shares”). The aggregate number of Shares which may be issued under
the Plan shall not exceed 4,000,000, unless an adjustment is required in
accordance with Article III.
2009
AMENDMENT TO
BIOTIME,
INC.
2002
STOCK OPTION PLAN
Effective
October 15, 2009, Article I, Section 4 is amended to read as
follows:
4.
SHARES OF STOCK SUBJECT TO
THE PLAN
The
shares that may be issued under the Plan shall be authorized and unissued or
reacquired common shares, no par value, of the Company (the
“Shares”). The aggregate number of Shares which may be issued under
the Plan shall not exceed 6,000,000, unless an adjustment is required in
accordance with Article III.
ex10_38.htm
Exhibit
10.38
STOCK
PURCHASE AGREEMENT
ONCOCYTE
CORPORATION
3,000,000
Common Shares
Price:
$0.667 per Share
READ THIS AGREEMENT
CAREFULLY BEFORE YOU INVEST
The
common shares, no par value (“Shares”) have not been registered under the
Securities Act of 1933, as amended, or applicable state securities laws and may
not be offered for sale, sold, transferred, pledged or hypothecated to any
person in the absence of an effective registration statement covering such
Shares (or an exemption from such registration) and an opinion of counsel
satisfactory to OncoCyte Corporation to the effect that such transfer or
exercise complies with applicable securities laws.
PURCHASE
AGREEMENT
This
Agreement is entered into by George Karfunkel (“Purchaser”) and OncoCyte
Corporation, a California corporation (the “Company).
1.
Purchase and
Sale of Shares.
(a)
Purchaser hereby irrevocably agrees to
purchase, and the Company agrees to sell to Purchaser, Three Million (3,000,000)
common shares, no par value (“Shares”) at the price of $0.667 per
Share.
(b)
This Agreement will become an irrevocable
obligation of Purchaser to purchase the number of Shares specified in paragraph
(a) of this Section 1, at the price of $0.667 per Share, when a copy of this
Agreement, signed by Purchaser, is countersigned by the
Company. Purchaser shall pay the purchase price of the Shares by wire
transfer to such account of the Company as the Company may
specify. If this Agreement is rejected or not accepted for any reason
by the Company, all sums paid by the Purchaser will be promptly returned,
without interest or deduction.
(c)
If Purchaser purchases the 3,000,000 Shares as
provided in paragraph (a) of this Section, by paying the purchase price in full,
Purchaser shall have the right, but not the obligation, to purchase from the
Company, on or before April 15, 2010, an additional Three Million (3,000,000)
Shares at the price of $0.667 per Share (subject to pro rata adjustment in the
event of any stock split, stock dividend, combination of shares, or other
recapitalization or reclassification of the Company’s common
shares). Purchaser may exercise the right to purchase such additional
Shares by giving the Company written notice of the exercise of such right
(“Exercise Notice”), and by paying the purchase price of such Shares in fully by
wire transfer to an account specified by the Company, which wire transfer shall
be made not later than the first business day after the Purchaser gives the
Company the Exercise Notice and the Company provides Purchaser with instructions
for wire transfer of the purchase price. By giving the Exercise
Notice specified in this paragraph, Purchaser shall irrevocably agree to
purchase 3,000,000 Shares at the price of $0.667 per Share.
2.
Registration
Rights. Concurrently with the execution and delivery of this
Agreement, Purchaser and the Company are entering into a Registration Rights
Agreement pursuant to which the Company is agreeing to register the Shares for
sale under the Securities Act of 1933, as amended (the “Act”).
3.
Investment
Representations. Purchaser represents and warrants to the
Company that:
(a)
Purchaser has made such investigation of the Company as
Purchaser deemed appropriate for determining to acquire (and thereby make an
investment in) the Shares. In making such investigation, Purchaser
has had access to such financial and other information concerning the Company as
Purchaser requested. Purchaser acknowledges and understands that the
Company is a start-up venture, without a history of operations, and has received
only limited capital from its controlling shareholder BioTime,
Inc. Purchaser acknowledges receipt of the Articles of Incorporation
and Bylaws of the Company, and copies of the minutes of the proceedings of the
Board of Directors of the Company. Purchaser has had a reasonable
opportunity to ask questions of and receive answers from the executive officers
of the Company concerning the Company, and to obtain such additional information
concerning the Company as may have been possessed or obtainable by the Company
without unreasonable effort or expense. All such questions have been answered to
Purchaser’s satisfaction.
(b)
Purchaser understands that the Shares are being offered and
sold without registration under the Act, or qualification under the California
Corporate Securities Law of 1968, or under the laws of any other states, in
reliance upon the exemptions from such registration and qualification
requirements for non-public offerings. Purchaser acknowledges and
understands that the availability of the aforesaid exemptions depends in part
upon the accuracy of certain of the representations, declarations and warranties
made by Purchaser, and the information provided by Purchaser, in this
Agreement, Purchaser is making such representations, declarations and
warranties, and is providing such information, with the intent that the same may
be relied upon by the Company and its officers and directors in determining
Purchaser’s suitability to acquire the Shares. Purchaser understands
and acknowledges that no federal, state or other agency has reviewed or endorsed
the offering of the Shares or made any finding or determination as to the
fairness of the offering or completeness of the information provided to
Purchaser by the Company.
(c)
Purchaser understands that the Shares may not be offered,
sold, or transferred in any manner unless subsequently registered under the Act,
or unless there is an exemption from such registration available for such offer,
sale or transfer.
(d)
Purchaser has such knowledge and experience in
financial and business matters to enable Purchaser to utilize the information
provided or otherwise made available to Purchaser by the Company to evaluate the
merits and risks of an investment in the Shares and to make an informed
investment decision.
(e)
Purchaser is acquiring the Shares solely for Purchaser’s
own account and for investment purposes, and not with a view to, or for sale in
connection with, any distribution of the Shares other than pursuant to an
effective registration statement under the Act or unless there is an exemption
from such registration available for such offer, sale or transfer, such as SEC
Rule 144.
(f)
Purchaser is an “accredited investor,” as such term is
defined in Regulation D promulgated under the Act.
(g)
Information provided to Purchaser by the Company include
matters that may be considered “forward looking” statements within the meaning
of Section 27(a) of the Act and Section 21(e) of the Securities Exchange Act of
1934, as amended (the “Exchange Act”), which statements Purchaser acknowledges
and agrees are not guarantees of future performance and involve a number of
risks and uncertainties, and with respect to which the Company makes no
representations or warranties. Purchaser understands that the level
of disclosure provided by the Company is less than that which would be provided
in a securities offering registered under the Act in reliance on the
sophistication and investment experience of Purchaser.
(h)
Purchaser understands that this Agreement and other
information provided to Purchaser by the Company contains confidential financial
information about the Company and BioTime, Inc. that has not yet been publicly
disclosed by the Company or BioTime, and therefore may be deemed material
non-public information, (2) the Company is providing Purchaser the confidential
information solely to satisfy its disclosure obligations under the Act in
connection with the offer and sale of the Shares to Purchaser pursuant to this
Agreement, and (3) until such time as BioTime files a Form 8-K or other report
under the Exchange Act with the Securities and Exchange Commission, Purchaser
shall not (A) disclose to any other person any of the information contained in
this Agreement or otherwise provided to Purchaser concerning the Company that
has not previously been disclosed in a report filed by BioTime under the
Exchange Act, or (B) purchase or sell any common shares or warrants of BioTime
other than shares purchased through the exercise of BioTime warrants already
held by Purchaser.
4.
Accredited Investor
Qualification. Purchaser qualifies as an “accredited investor”
under Regulation D in the following manner. (Please check or initial
all that apply
to verify that you qualify as an “accredited investor.”)
_____
(a)
|
Purchaser
is a natural person whose net worth, or joint net worth with spouse, at
the date of purchase exceeds $1,000,000 (including the value of home, home
furnishings, and automobiles).
|
_____
(b)
|
Purchaser
is a natural person whose individual
gross income (excluding that of spouse) exceeded $200,000 in each of the
past two calendar years, and who reasonably expects individual gross
income exceeding $200,000 in the current calendar
year.
|
_____
(c)
|
Purchaser
is a natural person whose joint gross
income with spouse exceeded $300,000 in each of the past two calendar
years, and who reasonably expects joint gross income with spouse exceeding
$300,000 in the current calendar
year.
|
_____
(d)
|
Purchaser
is a bank, savings and loan association, broker/dealer, insurance company,
investment company, pension plan or other entity defined in Rule 501(a)(1)
of Regulation D as promulgated under the Securities Act of 1933 by the
Securities and Exchange Commission.
|
_____
(e)
|
Purchaser
is a trust, and the trustee is a bank, savings and loan association, or
other institutional investor as defined in Rule 501(a)(1) of Regulation D
as promulgated under the Securities Act of 1933 by the Securities and
Exchange Commission.
|
_____
(f)
|
Purchaser
is a private business development company as defined in section 202(a)(22)
of the Investment Advisers Act of
1940.
|
_____
(g)
|
Purchaser
is a trust, and the grantor (i) has the power to revoke the trust at any
time and regain title to the trust assets; and (ii) meets the requirements
of items (a) (b), or (c) above.
|
_____
(h)
|
Purchaser
is a tax-exempt organization described in Section 501(c) (3) of the
Internal Revenue Code, or a corporation, Massachusetts or similar business
trust, or partnership, not formed for the specific purpose of acquiring
Shares with total assets in excess of
$5,000,000.
|
_____
(i)
|
The
Purchaser is a trust with total assets in excess of $5,000,000, not formed
for the specific purpose of acquiring Shares, whose purchase is directed
by a person who has such knowledge and experience in financial and
business matters that he is capable of evaluating the merits and risks of
an investment in the Shares.
|
_____
(j)
|
The
Purchaser is an entity in which all of the equity owners meet the
requirements of at least one of items (a) through (i)
above.
|
5.
Miscellaneous.
(a)
This Agreement shall be governed by, interpreted, construed
and enforced in accordance with the laws of the State of California, as such
laws are applied to contracts by and among residents of California, and which
are to be performed wholly within California.
(b)
The representations and warranties set forth herein
shall survive the sale of Shares to Purchaser.
(c)
Neither this Agreement nor any provisions hereof shall be
modified, discharged or terminated except by an instrument in writing signed by
the party against whom any waiver, change, discharge or termination is
sought.
(d) Any
notice, demand or other communication that any party hereto may be required, or
may elect, to give shall be sufficiently given if (i) deposited, postage
prepaid, in the United States mail addressed to such address as may be specified
under this Agreement, (ii) delivered personally at such address, (iii) delivered
to such address by air courier delivery service, or (iv) delivered by electronic
mail (email) to such electronic mail address as may be specified under this
Agreement. The address for notice to the Company is: OncoCyte
Corporation, 1301 Harbor Bay Parkway, Suite 100, Alameda, California 94502;
Attention: Steven Seinberg, Chief Financial Officer; email;
sseinberg@biotimemail.com. The address for notice of Purchaser is
shown in Section 6. Either party may change its address for notice by
giving the other party notice of a new address in the manner provided in this
Agreement. Any notice sent by mail shall be deemed given three days
after being deposited in the United States mail, postage paid, and addressed as
provided in this Agreement.
(e) This
Agreement may be executed through the use of separate signature pages or in any
number of counterparts, and each of such counterparts shall, for all purposes,
constitute one agreement binding on all the parties, notwithstanding that all
parties are not signatories to the same counterpart.
(f) Except
as otherwise provided herein, the Agreement shall be binding upon and inure to
the benefit of the parties and their heirs, executors, administrators,
successors, legal representatives and assigns. If the undersigned is
more than one person, the obligation of the undersigned shall be joint and
several and the agreements, representations, warranties and acknowledgments
herein contained shall be deemed to be made by and be binding upon each such
person and his heirs, executors, administrators and successors.
(g) This
instrument contains the entire agreement of the parties, and there are no
representations, covenants or other agreements except for those stated or
referred to herein.
(h) This
Agreement is not transferable or assignable by the undersigned except as may be
provided herein.
6.
Investor
Information.
(a)
|
Name:
|
|
|
|
|
(b)
|
Address:
|
|
|
|
|
(c)
|
email:
|
|
(e)
|
Social
Security Number:
|
|
|
or
Taxpayer Identification Number:
|
|
(f)
|
State
of Residence or Principal Place of Business:
|
|
IN
WITNESS WHEREOF, the undersigned has entered into this Agreement and hereby
agrees to purchase Shares for the price stated above and upon the terms and
conditions set forth herein. The undersigned hereby agrees to all of
the terms of the Registration Rights Agreement and agrees to be bound by the
terms and conditions thereof.
Dated:
October 15, 2009
|
/s/ George Karfunkel
|
|
|
George
Karfunkel
|
|
ACCEPTANCE BY
COMPANY
The
Company hereby agrees to sell to the Purchaser the Shares referenced above in
reliance upon all the representations, warranties, terms and conditions
contained in this Agreement.
IN
WITNESS WHEREOF, the undersigned, on behalf of the Company, has executed this
acceptance as of the date set forth below.
Dated: October
15, 2009
|
ONCOCYTE
CORPORATION
|
|
|
|
|
|
|
|
|
By:
/s/
Robert W. Peabody
|
|
|
|
|
|
Title:
Chief Operating
Officer
|
7
ex10_39.htm
Exhibit
10.39
REGISTRATION
RIGHTS AGREEMENT
This
Registration Rights Agreement (“Agreement”) is entered into as of October 15,
2009 by and between OncoCyte Corporation, a California corporation (the
“Company”) and the undersigned.
NOW,
THEREFORE, the parties agree as follows:
1.
Certain
Definitions. As used in this Agreement the following terms
shall have the following respective meanings:
(a)
“Act” shall mean the
Securities Act of 1933, as amended, or any similar federal statute and the rules
and regulations of the Commission thereunder, all as the same shall be in effect
at the time.
(b)
“Commission” shall
mean the Securities and Exchange Commission or any other federal agency at the
time administering the Act.
(c)
“Holder” shall mean
each person who originally purchased Registrable Securities from the Company
pursuant to a Stock Purchase Agreement and his/its transferees as permitted by
Section 6.
(d)
The terms “register,” “registered” and
“registration”
refer to a registration effected by preparing and filing a registration
statement in compliance with the Act, and the declaration or ordering of the
effectiveness of such registration statement.
(e)
“Registrable
Securities” means the Shares. Any securities that are (i)
distributed as a dividend or otherwise with respect to Registrable Securities,
(ii) issuable upon the exercise or conversion of Registrable Securities, or
(iii) issued or issuable in exchange for or through conversion of Registrable
Securities pursuant to a recapitalization, reorganization, merger, consolidation
or other transaction shall also constitute Registrable Securities.
(f)
“Shares” means up to
6,000,000 common shares, no par value, of the Company issued by the Company
pursuant to the Stock Purchase Agreement.
(g)
“Stock Purchase
Agreement” means a Stock Purchase Agreement pursuant to which the Company
agreed to issue and sell up to an aggregate of 6,000,000 Shares to the
undersigned.
2.
Registration
Rights.
(a)
Filing of Registration
Statement With Respect to Shares. The Company agrees, at its
expense, to file a registration statement with the Commission to register the
Shares under the Act, and to take such other actions as may be necessary to
allow the Shares to be freely tradable, without restrictions under the
Act. Such registration statement shall be filed following a written
request for registration from any Holder(s) of not less than 25% of the Shares
not earlier than one year after the Company completes an initial public offering
of its common shares registered under the Act (an “IPO”). The Company
will use commercially reasonable efforts to cause the registration statement to
become effective as promptly as practicable after filing. The Company
will make all filings required under applicable state securities or “blue sky”
laws so that the Registrable Securities being registered shall be registered or
qualified for sale under the securities or blue sky laws of New York,
California, and such jurisdictions as shall be reasonably appropriate for
distribution of the Shares covered by the registration statement. The
registration statement shall be a “shelf” registration pursuant to Rule 415 (or
similar rule that may be adopted by the Securities and Exchange Commission) and
shall provide that each Holder’s plan of distribution is to offer and sell
Shares from time to time at market prices or prices related to market prices;
provided, that a registration statement may be amended to provide for an
underwritten public offering of the Shares included in the registration
statement if the Holders submit to the Company a written notice to such effect
with a copy of the applicable underwriting documents and such other relevant
information concerning the offering as the Company may request. The
Company shall use commercially reasonable efforts to keep each such registration
statement effective until the earlier of (i) completion of the distribution or
distributions being made pursuant thereto, and (ii) such time as the Holders are
eligible to sell their Shares under Rule 144 under the Act without application
of the manner of sale and volume limitations under Rule 144. The
Company shall utilize Form S-3 if it qualifies for such use. The
Company will furnish to the Holders such numbers of copies of a prospectus,
including a preliminary prospectus, in conformity with the requirements of the
Act and such other related documents as the Holders may reasonably request in
order to effect the sale of their Shares.
(b)
“Piggy-Back Registration” of
Shares. If, at any time after the completion of an IPO, the
Company proposes to register any of its securities under the Act (otherwise than
pursuant to (i) this Agreement, (ii) a registration statement pertaining to
subscription rights distributed to Company shareholders, and (iii) a
registration on a Form S-8 or any other form if such form cannot be used for
registration of the Registrable Securities pursuant to its terms), and the
Shares shall not then be eligible for sale by the Holder(s) under Rule 144 under
the Act, the Company shall, as promptly as practicable, give written notice to
the Holders. The Company shall include in such registration statement
the Shares proposed to be sold by the Holders. Notwithstanding the
foregoing, if the offering of the Company’s securities is to be made through
underwriters, the Company shall not be required to include Shares if and to the
extent that the managing underwriter reasonably believes in good faith that such
inclusion would materially adversely affect such offering, unless the Holders
agree to postpone their sales until 10 days after the distribution is
completed. The provisions of Section 2(e) shall apply to any such
registration statement if the offering is made through
underwriters.
(c)
Costs of
Registration. The Company shall pay the cost of the
registration statements filed pursuant to this Agreement, including without
limitation all registration and filing fees, fees and expenses of compliance
with securities or blue sky laws (including counsel’s fees and expenses in
connection therewith), printing expenses, messenger and delivery expenses,
internal expenses of the Company, listing fees and expenses, and fees and
expenses of the Company’s counsel, independent accountants and other persons
retained or employed by the Company. Holders shall pay any
underwriters discounts applicable to the Registrable
Securities.
(d)
Other
Securities. Any registration statement filed pursuant to this
Agreement may include other securities of the Company which are held by other
persons who, by virtue of agreements with the Company or permission given, are
entitled to include their securities in such registration.
(e)
Underwriting. If
Holders wish to include Shares in a registration under Section 2(b), or if
Holders holding not less than 50% of the Shares intend to distribute Shares by
means of an underwriting to be registered under Section 2(a), they shall so
advise the Company prior to the effective date of the registration statement
filed by the Company, and the Company shall include such information in a
written notice to all Holders. All Holders shall be entitled to
participate in such underwriting, and the right of any Holder to registration
pursuant to this Agreement then shall be conditioned upon such Holder’s
participation in such underwriting and the inclusion of such Holder’s Shares in
the underwriting to the extent provided herein.
The
Company shall (together with all Holders proposing to distribute their
securities through such underwriting) enter into an underwriting agreement in
customary form with the managing underwriter selected for such underwriting by a
majority in interest of the Holders and reasonably acceptable to the Company, in
the case of a registration under Section 2(a), or selected by the Company is its
sole discretion, in the case of a registration under Section
2(b). Notwithstanding any other provision of this Agreement, if the
managing underwriter advises the Holders and the Company in writing that
marketing factors require a limitation of the number of shares to be
underwritten, then, the number of Registrable Securities that may be included in
the registration and underwriting shall be allocated among all Holders in
proportion, as nearly as practicable, to the respective amounts of Registrable
Securities held by such Holders and any other holders of securities having
rights to include their securities in the registration, at the time of filing
the registration statement. No Registrable Securities excluded from
the underwriting by reason of the managing underwriter’s marketing limitation
shall be included in such registration.
If any
Holder or any other holder of securities eligible for inclusion in the
registration disapproves of the terms of the underwriting, such person may elect
to withdraw from the underwriting and registration by written notice to the
Company and the managing underwriter. The Registrable Securities
and/or other securities so withdrawn shall also be withdrawn from the
registration; provided, however, that, if by the withdrawal of such Registrable
Securities or other securities a greater number of Registrable Securities held
by other Holders or other securities held by persons having rights to
participate in such registration may be included in such registration (up to the
maximum of any limitation imposed by the underwriters), then the Company shall
offer to all Holders and other persons who have included Registrable Securities
or other securities in the registration the right to include additional
Registrable Securities or other securities in the same proportion used in
determining the underwriter limitation.
Notwithstanding
any other provision of this Agreement, if the registration is one under Section
2(b), and the managing underwriter determines that marketing factors require a
limitation of the amount of securities to be underwritten, the Company may
exclude Registrable Securities and other securities held by other holders of
registration rights without any exclusion of securities offered by
Company. In the event of any exclusion of securities held by holders
of registration rights, the amount of securities that may be included in the
registration and underwriting shall be allocated among all Holders of
Registrable Securities and other holders of securities entitled to include
securities in such registration in proportion, as nearly as practicable, to the
respective amounts of Registrable Securities and other securities that the
Company has agreed to register held by each such person.
(f)
Waiver. Notwithstanding
any other provision of this Agreement the rights of the Holders under Section
2(b) may be waived by a majority-in-interest of the Holders (based upon their
holdings of Registrable Securities, with or without notice to the Holders
generally).
(g)
Limitation on Company
Liability. The Company shall have no obligation to make any
cash settlement or payment to any Holder, or to issue any additional Shares or
other securities to any Holder, in the event that the Company is unable to
effect or maintain in effect the registration of any Registrable Securities
under the Act or any state securities law despite the Company’s commercially
reasonable efforts so to do.
3.
Indemnification.
(a)
The Company will indemnify, defend and hold harmless
each Holder, each of its officers, directors and partners, and each person who
controls such Holder within the meaning of the Act, and each underwriter, if
any, and each person who controls any underwriter within the meaning of the Act
from and against all expenses, claims, losses, damages and liabilities (or
actions commenced or threatened in respect thereof), including any of the
foregoing incurred in settlement of any litigation commenced or threatened
(other than a settlement effected without the consent of the Company, which
consent will not unreasonably be withheld), to the extent such expenses, claims,
losses, damages and liabilities (or actions commenced or threatened in respect
thereof) arise out of or are based on (i) any untrue statement (or alleged
untrue statement) of a material fact contained in any registration statement or
prospectus, or any amendment or supplement thereto, offering Registrable
Securities, or any omission to state therein a material fact required to be
stated therein or necessary to make the statements therein, in light of the
circumstances in which they were made, not misleading, or (ii) any violation, by
the Company, of any rule or regulation promulgated under the Act and applicable
to the Company and relating to any registration of Registrable Securities by the
Company under the Act. The Company will reimburse each such Holder,
each of its officers, directors and partners, and each person controlling such
Holder, each such underwriter and each such person who controls any such
underwriter, for any legal and any other expenses reasonably incurred in
connection with investigating or defending any such claim, loss, damage,
liability or action; provided that the Company will not be liable in any such
case to the extent that any such claim, loss, damage, liability or expense
arises out of or is based on any untrue statement or omission based upon written
information furnished to the Company by such Holder or underwriter or
controlling person specifically for use in connection with the registration or
offering of Registrable Securities.
(b)
Each Holder will, if Registrable Securities held by such
Holder are included in a registration under the Act or under any state
securities law, indemnify, defend and hold harmless the Company, each of its
directors and officers, and each independent accountant of the Company, each
underwriter, if any, of the Company’s securities covered by such a registration
statement, each person who controls the Company or such underwriter within the
meaning of the Act, and each other such Holder, and each of the officers,
directors and partners and each person who controls such other Holder within the
meaning of the Act, from and against all claims, losses, damages and liabilities
(or actions commenced or threatened in respect thereof) arising out of or based
on (i) any untrue statement (or alleged untrue statement) of a material fact
contained in any such registration statement or prospectus, or any amendment or
supplement offering Registrable Securities, or any omission (or alleged
omission) to state therein a material fact required to be stated therein or
necessary to make the statements therein, in light of the circumstances in which
they were made, not misleading, or (ii) any violation, by such Holder, of any
rule or regulation promulgated under the Act applicable to such Holder and
relating to action or inaction required of such Holder in connection with any
registration of Registrable Securities. Such Holder will reimburse
the Company, such other Holders, such directors, officers, partners, persons,
accounting firms, underwriters, or control persons for any legal or any other
expenses reasonably incurred in connection with investigating or defending any
such claim, loss, damage, liability, or action, in each case to the extent, but
only to the extent, that such untrue statement (or alleged untrue statement) or
omission (or alleged omission) is made in such registration statement or
prospectus in reliance upon and in conformity with written information furnished
to the Company or any underwriter by such Holder specifically for use therein;
provided, however, that the obligations of such Holders under this Section 3(b)
shall be limited to an amount equal to the net proceeds to each such Holder from
the sale of Registrable Securities pursuant to such registration.
(c)
Each party entitled to indemnification under this Section 3
(the “Indemnified Party”) shall give notice to the party required to provide
indemnification (the “Indemnifying Party”) promptly after such Indemnified Party
has actual knowledge of any claim as to which indemnity may be sought, and shall
permit the Indemnifying Party to assume the defense of any such claim or any
litigation resulting therefrom; provided that counsel for the Indemnifying
Party, who shall conduct the defense of such claim or any litigation resulting
therefrom, shall be approved by the Indemnified Party (whose approval shall not
unreasonably be withheld). The Indemnified Party may participate in
such defense at the Indemnified Party’s own expense. The failure of
any Indemnified Party to give notice as provided herein shall not relieve the
Indemnifying Party of its obligations under this Section 3 except to the extent
such failure is prejudicial to the ability of the Indemnifying Party to defend
such action, but such failure shall not relieve the Indemnifying Party of any
liability that the Indemnifying Party may have to any Indemnified Party
otherwise than under this Section 3. No Indemnifying Party, in the
defense of any such claim or litigation, shall, except with the consent of each
Indemnified Party, consent to entry of any judgment or enter into any settlement
which does not include as an unconditional term thereof the giving by the
claimant or plaintiff to such Indemnified Party of a release from all liability
in respect to such claim or litigation.
4.
Information by
Holder. Each Holder of Registrable Securities included in any
registration shall furnish to the Company and to each underwriter, upon the
Company’s request, such information regarding such Holder and the distribution
proposed by such Holder as shall be required in connection with any registration
of Registrable Securities.
5.
Rule 144
Reporting. With a view to making available the benefits of
certain rules and regulations of the Commission which may permit the sale of the
Registrable Securities to the public without registration, the Company agrees
to:
(a)
Use commercially reasonable efforts to file
with the Commission in a timely manner all reports and other documents required
of the Company under the Securities Exchange Act of 1934, as amended (the
“Exchange Act”) at such times as the Company is subject to the reporting
requirements under Section 13 of the Exchange Act;
(b)
So long as a Holder owns any Registrable
Securities, furnish to the Holder forthwith upon request a written statement by
the Company as to its compliance with the reporting requirements of the Exchange
Act, a copy of the most recent annual or quarterly report of the Company, and
such other reports and documents so filed by the Company under the Exchange Act
as a Holder may reasonably request in availing itself of any rule or regulation
of the Commission allowing a Holder to sell any such securities without
registration.
6.
Transfer of Registration
Rights. The rights to cause the Company to register securities
under this Agreement may be assigned: (a) to an “affiliate” (defined
as an entity that controls, is controlled by, or under common control with the
transferor); (b) to one or more of its general partners, limited partners, or
members if the transferor is a partnership or limited liability company; or (c)
to any other transferee or assignee of an aggregate of twenty-five percent (25%)
or more of the transferor’s Registrable Securities; provided, that as a
condition to any transfer of such rights the transferor must give the Company
written notice at the time or within a reasonable time after said transfer,
stating its desire to transfer such rights, the name and address of the
transferee or assignee, and identifying the securities with respect to which
such registration rights are being assigned; provided, that nothing in this
Section shall be construed in any way to limit any restriction or condition on
transfer of any Registrable Securities imposed by any other agreement between a
Holder and the Company, the Act, any rule or regulation promulgated under the
Act, or any state securities or blue sky law or any rule or regulation
thereunder.
7.
Computation of Certain
Percentages. Where any provision of this Agreement provides
for the exercise, waive, or amendment of any rights upon the action of Holders
of a specified percentage of Registrable Securities, such percentage shall be
determined based upon the aggregate number of Registrable Securities issued and
outstanding.
8.
Miscellaneous.
(a)
Governing
Law. This Agreement shall be governed in all respects by the
laws of the State of California, as applied to contracts entered into in
California between California residents and to be performed entirely within
California.
(b)
Successors and
Assigns. Except as otherwise expressly provided herein, the
provisions hereof shall inure to the benefit of, and be binding upon, the
successors, assigns, heirs, executors and administrators of the parties
hereto.
(c)
Entire Agreement;
Amendment. This Agreement constitutes the full and entire
understanding and agreement between the parties with regard to the subject
matter hereof. Neither this Agreement nor any term hereof may be
amended, waived, discharged or terminated orally, but only by a written
instrument signed by the Company and Holders of a majority of the Registrable
Securities which have not been resold to the public.
(d)
Notices,
etc. All notices and other communications required or
permitted hereunder shall be in writing and shall be mailed by first-class mail,
postage prepaid, or otherwise delivered by hand, by messenger or next business
day air freight services, addressed (i) if to a Holder at such Holder’s address
set forth on the signature page hereto, or at such other address as such Holder
shall have furnished to the Company in writing, or (ii) if to the Company, at
1301 Harbor Bay Parkway, Suite 100, Alameda, California 94502;
attention: Chief Financial Officer, or at such other address as the
Company shall have furnished to the Holders in writing.
(e)
Delays or
Omissions. No delay or omission to exercise any right, power
or remedy accruing to any party, upon any breach or default of any other party
under this Agreement, shall impair any such right, power or remedy, nor shall it
be construed to be a waiver of or acquiescence in any such breach or default or
any similar breach or default thereafter occurring. A waiver of any
single breach or default shall not be deemed a waiver of any other breach or
default theretofore or thereafter occurring. Any waiver, permit,
consent or approval of any kind or character of any breach or default under this
Agreement, or any waiver of any provisions or conditions of this Agreement, must
be made in writing and shall be effective only to the extent specifically set
forth in such writing. All remedies, either under this Agreement, or
by law or otherwise afforded to any party, shall be cumulative and not
alternative.
(f)
Severability. In
case any provision of this Agreement shall be invalid, illegal or unenforceable,
the validity, legality and enforceability of the remaining provisions shall not
in any way be affected or impaired thereby.
(g)
Titles and
Subtitles. The titles of the sections and subparagraphs of
this Agreement are for convenience of reference only and are not to be
considered in construing this Agreement.
(h)
Counterparts. This
Agreement may be executed in any number of counterparts (including by separate
counterpart signature pages), each of which shall be an original, but all of
which together shall constitute one instrument. Any counterpart of
this Agreement may be signed by electronic or facsimile, and such electronic or
facsimile signature shall be deemed an original signature.
IN
WITNESS WHEREOF, the parties have executed this Agreement as of the date first
above written.
THE
COMPANY:
ONCOCYTE
CORPORATION
By
/s/ Robert
Peabody
Robert
Peabody,
Senior Vice
President and
Chief
Operating Officer
By
/s/ Judith
Segall
Judith
Segall, Secretary
HOLDER:
/s/
George Karfunkel
George
Karfunkel
Address
for Notice: 59 Maiden Lane
New York,
NY 10038
FAX: (718)
921-8340
9
ex31.htm
|
CERTIFICATIONS
|
Exhibit
31
|
I,
Michael D. West, certify that:
1. I
have reviewed this quarterly report on Form 10-Q of BioTime, Inc.
2. Based
on my knowledge, this report does not contain any untrue statement of a material
fact or omit to state a material fact necessary to make the statements made, in
light of the circumstances under which such statements were made, not misleading
with respect to the period covered by this report;
3. Based
on my knowledge, the financial statements, and other financial information
included in this report, fairly present in all material respects the financial
condition, results of operations and cash flows of the registrant as of, and
for, the periods presented in this report;
4. The
registrant’s other certifying officers and I are responsible for establishing
and maintaining disclosure controls and procedures (as defined in Exchange Act
Rule 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as
defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and
have:
|
(a)
|
Designed
such disclosure controls and procedures, or caused such disclosure
controls and procedures to be designed under our supervision, to ensure
that material information relating to the registrant, including its
consolidated subsidiaries, is made known to us by others within those
entities, particularly during the period in which the periodic reports are
being prepared;
|
|
(b)
|
Designed
such internal control over financial reporting, or caused such internal
control over financial reporting to be designed under our supervision, to
provide reasonable assurance regarding the reliability of financial
reporting and the preparation of financial statements for external
purposes in accordance with generally accepted accounting
principles
|
|
(c)
|
Evaluated
the effectiveness of the registrant’s disclosure controls and procedures
and presented in this report our conclusions about the effectiveness of
the disclosure controls and procedures, as of the end of the period
covered by this report based on such evaluation;
and
|
|
(d)
|
Disclosed
in this report any change in the registrant’s internal control over
financial reporting that occurred during the registrant’s most recent
fiscal quarter that has materially affected, or is reasonably likely to
materially affect, the registrant’s internal control over financial
reporting.
|
5. The
registrant's other certifying officers and I have disclosed, based on our most
recent evaluation of internal control over financial reporting, to the
registrant's auditors and the audit committee of registrant's board of directors
(or persons performing the equivalent functions):
|
(a)
|
All
significant deficiencies and material weaknesses in the design or
operation of internal control over financial reporting which are
reasonably likely to adversely affect the registrant's ability to record,
process, summarize and report financial information;
and
|
|
(b)
|
Any
fraud, whether or not material, that involves management or other
employees who have a significant role in the registrant's internal control
over financial reporting.
|
Date: November
12, 2009
/s/ Michael D. West
|
|
Michael
D. West
|
|
Chief
Executive Officer
|
|
|
CERTIFICATIONS
|
Exhibit
31
|
I, Steven
Seinberg, certify that:
1. I
have reviewed this quarterly report on Form 10-Q of BioTime, Inc.
2. Based
on my knowledge, this report does not contain any untrue statement of a material
fact or omit to state a material fact necessary to make the statements made, in
light of the circumstances under which such statements were made, not misleading
with respect to the period covered by this report;
3. Based
on my knowledge, the financial statements, and other financial information
included in this report, fairly present in all material respects the financial
condition, results of operations and cash flows of the registrant as of, and
for, the periods presented in this report;
4. The
registrant’s other certifying officers and I are responsible for establishing
and maintaining disclosure controls and procedures (as defined in Exchange Act
Rule 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as
defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and
have:
|
(e)
|
Designed
such disclosure controls and procedures, or caused such disclosure
controls and procedures to be designed under our supervision, to ensure
that material information relating to the registrant, including its
consolidated subsidiaries, is made known to us by others within those
entities, particularly during the period in which the periodic reports are
being prepared;
|
|
(f)
|
Designed
such internal control over financial reporting, or caused such internal
control over financial reporting to be designed under our supervision, to
provide reasonable assurance regarding the reliability of financial
reporting and the preparation of financial statements for external
purposes in accordance with generally accepted accounting
principles
|
|
(g)
|
Evaluated
the effectiveness of the registrant’s disclosure controls and procedures
and presented in this report our conclusions about the effectiveness of
the disclosure controls and procedures, as of the end of the period
covered by this report based on such evaluation;
and
|
|
(h)
|
Disclosed
in this report any change in the registrant’s internal control over
financial reporting that occurred during the registrant’s most recent
fiscal quarter that has materially affected, or is reasonably likely to
materially affect, the registrant’s internal control over financial
reporting.
|
5. The
registrant's other certifying officers and I have disclosed, based on our most
recent evaluation of internal control over financial reporting, to the
registrant's auditors and the audit committee of registrant's board of directors
(or persons performing the equivalent functions):
|
(c)
|
All
significant deficiencies and material weaknesses in the design or
operation of internal control over financial reporting which are
reasonably likely to adversely affect the registrant's ability to record,
process, summarize and report financial information;
and
|
|
(d)
|
Any
fraud, whether or not material, that involves management or other
employees who have a significant role in the registrant's internal control
over financial reporting.
|
Date: November
12, 2009
/s/ Steven A. Seinberg
|
|
Steven
A. Seinberg
|
|
Chief
Financial Officer
|
|
ex32.htm
Exhibit
32
CERTIFICATION
PURSUANT TO 18 U.S.C. SECTION 1350,
AS
ADOPTED PURSUANT TO
SECTION
906 OF THE SARBANES-OXLEY ACT OF 2002
In
connection with the Quarterly Report on Form 10-Q of BioTime, Inc. (the
“Company”) for the quarter ended September 30, 2009 as filed with the Securities
and Exchange Commission on the date hereof (the “Report”), we, Michael D. West,
Chief Executive Officer, and Steven A. Seinberg, Chief Financial Officer of the
Company, certify pursuant to 18 U.S.C. Section 1350, as adopted pursuant to
Section 906 of the Sarbanes-Oxley Act of 2002, that:
1. The
Report fully complies with the requirements of Section 13(a) or 15(d) of the
Securities Exchange Act of 1934, as amended; and
2. The
information contained in the Report fairly presents, in all material respects,
the financial condition and results of operations of the Company.
Date:
November 12, 2009
/s/ Michael D. West
|
|
Michael
D. West
|
|
Chief
Executive Officer
|
|
|
|
|
|
/s/ Steven A. Seinberg
|
|
Steven
A. Seinberg
|
|
Chief
Financial Officer
|
|